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Overview of Dermatological Manifestations Associated with the COVID-19 Infection.
Skin Therapy Lett
March 2024
Center for Dermatology Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Article Synopsis
- COVID-19, caused by the SARS-CoV-2 virus, primarily presents with respiratory symptoms, fever, and chills, but it can also cause skin-related issues in some patients.
- Dermatological symptoms include various types of lesions, such as chilblain-like, maculopapular, and necrotic lesions, but the exact reasons for these skin reactions remain unclear.
- The review seeks to gather and analyze past studies and case reports to better understand these skin manifestations and identify areas for future research.
Bullous pemphigoid (BP) appears to be rising in incidence across the Western World, especially in the elderly. Some of the pathogenetic mechanisms involving antigen mimicry and antibody cross-reactivity have been elucidated for cases associated with neurological disease and certain drugs. There have been reports of cutaneous manifestations of Covid-19 (SARS-Cov2 infection) as the pandemic has raged across the world.
View Article and Find Full Text PDFConcurrent chilblains and retinal vasculitis in a child with COVID-19.
J Eur Acad Dermatol Venereol
December 2020
Department of Dermatology, University Hospital La Paz, Madrid, Spain.
Severe recalcitrant cutaneous manifestations in systemic lupus erythematosus successfully treated with fumaric acid esters.
Br J Dermatol
February 2017
Department of Dermatology, The Royal Free London NHS Foundation Trust, London, U.K.
Fumaric acid esters (FAEs) have proven efficacy in the treatment of psoriasis and have been in use for decades. More recently, as their mechanism of action and abundant immunomodulatory effects become clearer, the potential benefits of treating other inflammatory skin conditions using FAEs are increasingly being recognized. The use of FAEs as combination systemic therapy has not been well studied and data are lacking regarding the safety and efficacy of this type of therapy.
View Article and Find Full Text PDFChilblains and microgeodic disease diagnosed concurrently in a child's toe.
Pediatr Dermatol
September 2013
Department of Pediatrics, Yale New Haven Hospital, New Haven, Connecticut 06510, USA.
Microgeodic disease, similar to chilblains (pernio), is characterized by painful, erythematous swelling, as well as small, punched-out erosions found in affected phalanges. Although they share a similar appearance and proposed pathogenesis, chilblains has rarely been diagnosed in children with microgeodic disease, and in those cases has not been confirmed on skin biopsy. This article details a child in Connecticut diagnosed during the winter with chilblains and microgeodic disease of his toe, as supported by biopsy and imaging.
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