AI Article Synopsis
- The study examined the impact of in ovo feeding (IOF) N-acetyl-L-glutamate (NAG) on broiler chickens' early growth and intestinal development, using 702 fertilized eggs divided into three groups.
- The results showed that while hatchability was unaffected, chicks injected with NAG had lower average daily feed intake and feed conversion ratios in the first two weeks compared to controls.
- NAG injection improved certain intestinal characteristics, like increased goblet cell density and villus height, suggesting enhanced immune and absorption function in young broilers, positively influencing feed efficiency.
Article Abstract
The present study determined the effects of in ovo feeding (IOF) of N-acetyl-L-glutamate (NAG) on early intestinal development and growth performance of broilers. A total of 702 fertile broiler eggs were randomly divided into 3 treatments: 1) non-punctured control group, 2) saline-injected control group, and 3) NAG solution-injected group (1.5 mg/egg). At 17.5 D of incubation, 300 μL of each solution was injected into each egg of injected groups. Results indicated that the hatchability and healthy chicken rate were not affected by NAG injection (P > 0.05). Chicks from NAG solution-injected group had significantly decreased average daily feed intake and feed conversion ratio during 1-14 D than those in the non-punctured control group (P < 0.05). Compared with the non-punctured control group, IOF of NAG significantly increased the density of goblet cells in jejunum at hatch, duodenum at 7 D, and ileum at 14 D; decreased crypt depth in jejunum at hatch; and increased villus height in duodenum and jejunum and villus height:crypt depth ratio in duodenum at 7 D (P < 0.05). The intestinal mRNA expression of Na-dependent neutral amino acid transporter, peptide transporter, and excitatory amino acid transporter 3 did not differ between groups at 7 or 14 D. However, the mRNA expression level of rBAT in jejunum significantly increased in the NAG solution-injected group than in the non-punctured control group at 7 D (P < 0.05). In conclusion, IOF of NAG (1.5 mg/egg) accelerated the early intestinal development by enhancing intestinal immune and absorption function, thereby positively affecting the feed efficiency for the first 2 wk post-hatch.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7597834 | PMC |
| http://dx.doi.org/10.1016/j.psj.2020.04.003 | DOI Listing |
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