Background: Infantile intracranial aneurysms (IAs) are extremely rare. IA clipping and embolization have been the most common treatment options. Infantile giant IAs treated by surgical resection and in situ anastomosis have rarely been reported.
Case Description: A 43-day-old female infant was admitted to our hospital because of abnormal crying and vomiting. Multimodal images showed a right temporal hematoma and a giant dissecting IA. With comprehensive preoperative management, IA resection and in situ anastomosis were successfully performed. Furthermore, intraoperative and postoperative multimodal images demonstrated that the parent vessel was patent. Pathological examination showed chronic inflammation of this IA wall. The infant had a favorable outcome during the 3-month follow-up period.
Conclusions: Infantile giant IAs are extremely rare. Chronic inflammation might be involved in the pathogenesis of infantile dissecting IAs. IA resection and in situ anastomosis could be a reasonable choice in the management of infantile giant IAs that cannot be completely clipped or embolized.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.wneu.2020.06.201 | DOI Listing |
Diseases
December 2024
Department of Pediatrics, Dokkyo Medical University, Tochigi 321-0293, Japan.
Background: Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mutations in the TSC1 and TSC2 genes, leading to the dysregulation of the mammalian target of rapamycin (mTOR) pathway. This dysregulation results in the development of benign tumors across multiple organ systems and poses significant neurodevelopmental challenges. The clinical manifestations of TSC vary widely and include subependymal giant cell astrocytomas (SEGAs), renal angiomyolipomas (AMLs), facial angiofibromas (FAs), and neuropsychiatric conditions such as autism spectrum disorder (ASD).
View Article and Find Full Text PDFFront Pediatr
December 2024
Department of Neonatal Surgery, Shanxi Provincial Children's Hospital, Taiyuan, China.
Background: Intrathoracic kidney (ITK) is a rare congenital disease, with only about 40 pediatric cases reported worldwide to date. ITK associated with congenital diaphragmatic hernia (CDH) is even rarer, and we report a case of an infant with ITK combined with a giant CDH.
Case Description And Management: A six-month-old male infant was hospitalized due to "vomiting for 4 days".
Saudi Med J
November 2024
From the Department of Pediatrics (Aden, Fawzi), Division of Neurology; from the Department of Pathology (Prosser), Division of Pathology Genetics; from the Child and Adolescent Mental Health Services (Ather); from the Department of Anatomical imaging (Raja, Ederies), Division of Neuroradiology; from the Department of Surgery (Al-Kharazi), Division of Neurosurgery; and from the Department of Pediatrics (Maaz), Division of Hematology/Oncology, Sidra Medicine, Doha, Qatar.
Objectives: To review the clinical and radiological correlation of the central nervous system manifestations of tuberous sclerosis complex (TSC).
Methods: All patients under the age of 18 years with TSC seen at the Department of Pediatrics, Sidra Medicine, Doha, Qatar, between January 2003 and February 2021 were included in this retrospective study. Severity of epilepsy was determined using the early childhood epilepsy severity score (E-CHESS) tool.
Semin Pediatr Neurol
October 2024
Department of Neurology, The University of Texas at Austin Dell Medical School, Austin, TX. Electronic address:
J Dermatolog Treat
December 2024
Shimducktaik Dermatology Clinic, Bundang, Korea.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!