Three anthraquinone analogues (-) were isolated by phytochemical work on EtOAc-soluble ingredients extracted from the roots of . The structures of all isolates were elucidated by NMR, MS and CD experiments, of which (polygodoquinone A) was identified as a new anthraquinone derivative. Specifically, represents an unusual structure composed of a naphthoquinone derivative linked to an anthraquinone via a C-C bond. - exhibited remarkable influenza A virus inhibitory activity with IC values of 11.4, 11.0, and 2.3 μM, respectively, which were better than ribavirin as the positive control.
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