Two new milbemycin derivatives from a genetically engineered strain .

J Asian Nat Prod Res

Key Laboratory of Vector Biology and Pathogen Control of Zhejiang Province, College of Life Science, Huzhou University, Huzhou 313000, China.

Published: July 2021

Two new milbemycin derivatives, milbemycin M () and milbemycin N (), were isolated from the culture of a genetically engineered strain BCJ60. Their structures were elucidated through the interpretation of NMR and HR-ESI-MS spectroscopic data, as well as comparison with previous reports. The acaricidal and nematicidal activities of them against and were tested. The results showed that compounds - possessed potent acaricidal and nematocidal activities.

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Source
http://dx.doi.org/10.1080/10286020.2020.1783656DOI Listing

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