The original version of this article unfortunately contained a careless error in Fig. 2b-c, where the pictures of group Vehicle were the same with group VEGF.
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Paired Remote Ischemic Preconditioning in Recipients and Living Donors Can Mitigate Cardiovascular Stress in Recipients After Living-Donor Kidney Transplantation: A Propensity-Score-Matching Analysis.
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Department of Anesthesiology and Pain Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
: This study explored the effect of paired remote ischemic preconditioning (RIPC), involving both recipients and living donors, on cardiovascular stress in recipients after living-donor kidney transplantation (LDKT). The analysis included an assessment of the impact on cardiovascular biomarkers and post-transplant cardiovascular clinical events. : A retrospective observational cohort study of 520 adult LDKT patients was conducted, employing propensity score matching (PSM) to analyze perioperative factors.
View Article and Find Full Text PDFQuantitative brain [F]FDG PET beyond normal blood glucose levels.
Neuroimage
October 2024
Molecular Imaging Biomarkers Group. Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), University of Santiago de Compostela (USC), Campus Vida, Santiago de Compostela, Galicia, Spain; Nuclear Medicine Department and Molecular Imaging Biomarkers Group, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain. Electronic address:
Introduction SUV measurements from static brain [F]FDG PET acquisitions are a commonly used tool in preclinical research, providing a simple alternative for kinetic modelling, which requires complex and time-consuming dynamic acquisitions. However, SUV can be severely affected by the animal handling and preconditioning protocols, primarily by those that may induce changes in blood glucose levels (BGL). Here, we aimed at developing and investigating the feasibility of SUV-based approaches for a wide range of BGL far beyond normal values, and consequently, to develop and validate a new model to generate standardized and reproducible SUV measurements for any BGL.
View Article and Find Full Text PDFAerobic interval training preconditioning protocols inhibit isoproterenol-induced pathological cardiac remodeling in rats: Implications on oxidative balance, autophagy, and apoptosis.
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This study aimed to investigate the potential cardioprotective effects of moderate and high-intensity aerobic interval training (MIIT and HIIT) preconditioning. The focus was on histological changes, pro-oxidant-antioxidant balance, autophagy initiation, and apoptosis in myocardial tissue incited by isoproterenol-induced pathological cardiac remodeling (ISO-induced PCR). Male Wistar rats were randomly divided into control ( = 6), ISO ( = 8), MIIT ( = 4), HIIT ( = 4), MIIT + ISO ( = 8), and HIIT + ISO ( = 8) groups.
View Article and Find Full Text PDFAddressing the implementation challenge of risk prediction model due to missing risk factors: The submodel approximation approach.
Stat Med
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Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee.
Article Synopsis
- Clinical prediction models are valuable tools intended to improve clinical decision making, but their use in practice is limited due to issues like incomplete data in electronic health records (EHR).
- The article proposes a new submodel approach that enhances prediction model application by refining the model coefficients to better handle real-time data inconsistencies.
- Simulation results indicate that this new method performs well across different scenarios and is better suited for practical implementation than existing methods, specifically in identifying emergency department patients with acute heart failure eligible for safe discharge.
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