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Cytomegalovirus Infections in Patients Diagnosed with Inflammatory Bowel Disease.
Infect Dis Clin Microbiol
December 2024
Department of Infectious Diseases and Clinical Microbiology, Ankara University School of Medicine, Ankara, Türkiye.
Objective: The impact of cytomegalovirus (CMV) on inflammatory bowel disease (IBD) flares remains a matter of debate. This study aimed to evaluate patients with CMV infection who presented with IBD exacerbation in terms of diagnosis and treatment and investigate the importance of CMV DNA levels in colitis development.
Materials And Methods: Patients who were followed up with IBD and examined with clinical suspicion of CMV colitis at a university hospital between January 2016 and December 2021 were retrospectively scanned.
Enhanced pathogenicity and synergistic effects of co-infection with bovine viral diarrhea virus 1 and HoBi-like virus in cattle and guinea pigs.
Front Vet Sci
November 2024
The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, China.
Introduction: The Bovine Viral Diarrhea Virus 1 (BVDV1) and HoBi-like virus (BVDV3), both within the same genus, share genomic homology and exhibit low antigenic cross-reactivity despite presenting similar clinical manifestations. In 2021, a bovine respiratory disease complex (BRDC) outbreak on two cattle farms in the Inner Mongolia Autonomous Region of China resulted in ten fatalities.
Methods: Metagenomic and metatranscriptomic analyses were used to identify viral agents, including a co-infection case.
The Impact of Cytomegalovirus Infection on Ulcerative Colitis Relapse: A Multicenter Retrospective Cohort Study.
J Inflamm Res
November 2024
Department of Gastroenterology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu Province, People's Republic of China.
Purpose: Cytomegalovirus (CMV) infection exacerbates intestinal inflammation in ulcerative colitis (UC) patients, yet the effect of CMV infection on UC relapse has not been fully elucidated. This study aimed to investigate the impact of CMV infection on UC relapse and identify associated risk factors.
Patients And Methods: This multicenter retrospective cohort study included UC patients who visited research centers from January 2016 to December 2020.
Prevalence and clinical-epidemiological characteristics of chronic hepatitis due to hepatitis delta virus on Gran Canaria Island.
Enferm Infecc Microbiol Clin (Engl Ed)
November 2024
Servicio de Microbiología, Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Spain. Electronic address:
Article Synopsis
- The study aimed to determine the prevalence and characteristics of patients with chronic hepatitis D virus (HDV) infection from a hospital in 2023.
- Out of 340 patients with HBsAg, 24 (7.1%) tested positive for anti-HDV antibodies, and 6 (25%) were found to have chronic HDV infection, indicating a low prevalence of chronic HDV hepatitis (1.8%).
- Most patients with chronic infection had advanced disease, with significant rates of cirrhosis (83.3%) and hepatocellular carcinoma (33.3%); those without active viremia likely resolved their infection over an average of 13.5 years of follow-up.
Chemokine receptors in COVID-19 infection.
Int Rev Cell Mol Biol
September 2024
Universidad Nacional de San Agustín de Arequipa, Arequipa, Peru. Electronic address:
Chemokine receptors play diverse roles in the immune response against pathogens by recruiting innate and adaptive immune cells to sites of infection. However, their involvement could also be detrimental, causing tissue damage and exacerbating respiratory diseases by triggering histological alterations such as fibrosis and remodeling. This chapter reviews the role of chemokine receptors in the immune defense against SARS-CoV-2 infection.
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