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Comparison of Alcohol Septal Ablation with Mavacamten in Obstructive Hypertrophic Cardiomyopathy.
Am J Cardiol
December 2024
Northwestern University, Feinberg School of Medicine, Chicago IL 60611; The Hypertrophic Cardiomyopathy Program at the Bluhm Cardiovascular Institute, Chicago IL 60611; Bluhm Cardiovascular Institute, Northwestern Memorial Hospital, Chicago IL 60611.
Background: Obstructive hypertrophic cardiomyopathy (HCM) is associated with significant morbidity due to left ventricular outflow tract (LVOT) obstruction. While alcohol septal ablation (ASA) is an established interventional treatment, mavacamten, a novel cardiac myosin inhibitor, has emerged as a non-invasive pharmacological alternative. Understanding the comparative efficacy of these two treatments is important for optimizing patient care.
View Article and Find Full Text PDFComplete percutaneous repair of Tetralogy of Fallot in adult: a case report.
J Cardiothorac Surg
December 2024
Department of Cardiology, IPGMER and SSKM Hospital, Flat B1, GB 43, Narayantala West, D. B. Nagar, Kolkata, 700059, India.
Tetralogy of Fallot (TOF) is the most common congenital cyanotic heart disease and is characterized by an antero-superior deviation of the infundibular septum with a consequent large malaligned ventricular septal defect (VSD) and a pulmonary and sub-pulmonary (infundibular) stenosis. Surgical repair has been the cornerstone of treatment that is electively performed early in their lives between 3 and 6 months of age. With advancements in transcatheter interventions, the complete percutaneous repair of TOF, a complex disease with multiple treatable lesions, is becoming a conceivable possibility.
View Article and Find Full Text PDF[Replacement of Left Atrioventricular Valve and Patch Augmentation of Right Atrioventricular Valve After Repair of Complete Atrioventricular Septal Defect:Report of a Case].
Kyobu Geka
November 2024
Department of Cardiovascular Surgery, Saitama Children's Medical Center, Saitama, Japan.
Reoperations can be challenging for patients who experience left and right atrioventricular valve failure after repair of a complete atrioventricular septal defect. Herein, we present a case of a 10-year-old boy who developed dysfunction in left and right atrioventricular valve following surgery for a complete atrioventricular septal defect. The patient underwent successful replacement of his left atrioventricular valve with a mechanical valve due to severe stenosis.
View Article and Find Full Text PDFNeurohormonal activation pattern in patients with atrial septal defect.
Sci Rep
December 2024
Medeniyet Üniversitesi Kardiyoloji Anabilim Dalı, İstanbul, Turkey.
Atrial septal defects (ASD) divert flow from systemic to pulmonary circulation, and some degree of plasma volume expansion and neurohormonal activation are necessary to maintain the effective circulatory volume. The aim of the present study was to understand the patterns of neurohormonal activation in ASD patients. 16 ASD patients and 10 controls were enrolled.
View Article and Find Full Text PDFIntramural Ventricular Arrhythmias: How to Crack a Hard Nut.
Curr Cardiol Rep
December 2024
Section of Cardiac Electrophysiology, Hospital of the University of Pennsylvania, 1 Convention Avenue, Philadelphia, Pennsylvania, 19104, USA.
Article Synopsis
- * Mapping procedures, especially in regions like the left ventricular ostium and interventricular septum, are essential for pinpointing intramural arrhythmias and planning appropriate ablation strategies.
- * Advanced techniques, such as bipolar ablation or transvenous ethanol injection, may be necessary during ablation, highlighting the importance of comprehensive mapping that includes the coronary venous system.
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