AI Article Synopsis

  • The Jat Sikh population of Punjab, a large endogamous group in India, has been under-researched for genetic variations linked to X-STR markers.
  • The study aimed to analyze the genetic diversity of 12 X chromosomal STR markers among 200 Jat Sikh individuals (100 males and 100 females) to enhance the existing X-STR polymorphism database.
  • Results indicated that the marker DXS10135 showed the highest discrimination power for both genders, suggesting its potential application in forensic and genealogical contexts.

Article Abstract

Background: The Jat Sikh population is the largest endogamous group of Punjab, a state in north-west India, and has not yet been explored for genetic polymorphism based on X-STR genetic markers. In India, which is the second most populous country in the world, only two population studies based on X-STR markers have been reported so far.

Aim: To explore the genetic diversity of 12 X chromosomal STR genetic markers in the Jat Sikh population of Punjab and expand the X-STR polymorphism database.

Subjects And Methods: In this study, a total of 200 Jat Sikh individuals (100 males and 100 females) residing in Punjab were investigated for 12 X-STR markers using the Investigator Argus X-12 QS Kit.

Results: The highest power of discrimination (PD) in females (PD) and males (PD) was observed to be 0.965 (DXS10135) and 0.929 (DXS10135 and DXS10148), respectively. DXS10135 was found to be the most polymorphic and discriminating locus among all the studied loci in both males and females with highest values of power of discrimination (PD) and polymorphic information content (PIC) as well.

Conclusion: Overall, the studied markers of the Argus 12 X-STR kit provide high polymorphic information which may prove to be an important tool in resolving issues such as missing person identification, incest, immigration disputes, kinship analysis and genealogical studies. The dataset obtained from this study will add to the present database of X-STRs.

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http://dx.doi.org/10.1080/03014460.2020.1772876DOI Listing

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Article Synopsis
  • The Jat Sikh population of Punjab, a large endogamous group in India, has been under-researched for genetic variations linked to X-STR markers.
  • The study aimed to analyze the genetic diversity of 12 X chromosomal STR markers among 200 Jat Sikh individuals (100 males and 100 females) to enhance the existing X-STR polymorphism database.
  • Results indicated that the marker DXS10135 showed the highest discrimination power for both genders, suggesting its potential application in forensic and genealogical contexts.
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