AI Article Synopsis

  • The study focused on the occurrence of infections caused by extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-PE) compared to non-ESBL-PE infections in patients already colonized with ESBL-PE.
  • Findings indicated that most infections in these colonized patients are not caused by ESBL-PE, meaning that these bacteria are not the main culprits in most cases.
  • The research suggests that understanding where the infection occurs and patient-specific factors could help predict non-ESBL-PE infections, which could improve treatment decisions.

Article Abstract

We investigated relative proportions of extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-PE) versus non-ESBL-PE (nESBL-PE) infections in ESBL-PE colonized patients. ESBL-PE are not causative for the majority of infections in hospitalized patients colonized with ESBL-PE. Site of infection and patient-level exposures may be useful predictors of nESBL-PE infections, potentially guiding empiric treatment recommendations.

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http://dx.doi.org/10.1093/cid/ciaa895DOI Listing

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