AI Article Synopsis

  • Time-resolved studies on mechanochemical cocrystallisation have mainly looked at neat and liquid-assisted grinding.
  • This report investigates polymer-assisted grinding and finds that it significantly speeds up the reaction rate, nearly doubling it compared to neat grinding.
  • Interestingly, the reaction rate remains consistent regardless of the polymer's molecular weight or the amount used.

Article Abstract

Time-resolved mechanochemical cocrystallisation studies have so-far focused solely on neat and liquid-assisted grinding. Here, we report the investigation of polymer-assisted grinding reactions using in situ X-ray powder diffraction, revealing that reaction rate is almost double compared to neat grinding and independent of the molecular weight and amount of the polymer additive used.

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http://dx.doi.org/10.1039/d0cc03460fDOI Listing

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Article Synopsis
  • Time-resolved studies on mechanochemical cocrystallisation have mainly looked at neat and liquid-assisted grinding.
  • This report investigates polymer-assisted grinding and finds that it significantly speeds up the reaction rate, nearly doubling it compared to neat grinding.
  • Interestingly, the reaction rate remains consistent regardless of the polymer's molecular weight or the amount used.
View Article and Find Full Text PDF

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