Juvenile gangrenous vasculitis of the scrotum is a rare entity of unknown aetiology which should be considered in the differential diagnosis of genital ulcers, mainly with those caused by sexually transmitted infections. The authors report a case of a 23-year-old patient who presented a single painful scrotal ulcer developing shortly after an episode of pharyngotonsillitis. The ulcer was treated with oral corticosteroids with total healing and no relapse in over two years of follow-up.
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http://dx.doi.org/10.1111/ajd.13373 | DOI Listing |
Ital J Dermatol Venerol
December 2024
Department of Dermatology, Istituto Dermopatico dell'Immacolata (IDI-IRCCS), Rome, Italy -
Postgrad Med J
September 2024
Department of Medical Microbiology, Harran University Medical Faculty, Şanlıurfa 63000, Turkey.
Ann Dermatol
May 2023
Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Juvenile gangrenous vasculitis is characterized by the abrupt onset of scrotal ulcerations in young males, preceded by fever and pharyngeal symptoms. The etiology of this disease is poorly understood. The course is benign and self-limiting within a few weeks with no relapse.
View Article and Find Full Text PDFBMC Med Res Methodol
May 2023
Medialis Ltd, 3 Warren Yard, Wolverton Mill, Milton Keynes, MK12 5NW, UK.
Background: There is a pressing need to improve the accuracy of rare disease clinical study endpoints. Neutral theory, first described here, can be used to assess the accuracy of endpoints and improve their selection in rare disease clinical studies, reducing the risk of patient misclassification.
Methods: Neutral theory was used to assess the accuracy of rare disease clinical study endpoints and the resulting probability of false positive and false negative classifications at different disease prevalence rates.
Arch Rheumatol
December 2021
Rheumatology, Cairo University, Faculty of Medicine, Cairo, Egypt.
Objectives: This study aims to examine the frequency and clinical association of lupus-related vasculitis in patients with systemic lupus erythematosus (SLE).
Patients And Methods: We retrospectively analyzed medical records of a total of 565 SLE patients (42 males, 523 females; mean age: 32.7±9.
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