AI Article Synopsis

Article Abstract

Juvenile gangrenous vasculitis of the scrotum is a rare entity of unknown aetiology which should be considered in the differential diagnosis of genital ulcers, mainly with those caused by sexually transmitted infections. The authors report a case of a 23-year-old patient who presented a single painful scrotal ulcer developing shortly after an episode of pharyngotonsillitis. The ulcer was treated with oral corticosteroids with total healing and no relapse in over two years of follow-up.

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajd.13373DOI Listing

Publication Analysis

Top Keywords

juvenile gangrenous
8
gangrenous vasculitis
8
vasculitis scrotum
8
scrotum rare
8
rare genital
4
genital ulcer
4
ulcer juvenile
4
rare entity
4
entity unknown
4
unknown aetiology
4

Similar Publications

Many faces of cutaneous leishmaniasis.

Postgrad Med J

September 2024

Department of Medical Microbiology, Harran University Medical Faculty, Şanlıurfa 63000, Turkey.

Article Synopsis
  • This study aimed to identify atypical clinical presentations of cutaneous leishmaniasis (CL) in Şanlıurfa province, encompassing a retrospective analysis of 213 patients with non-standard symptoms out of 1,751 diagnosed cases between 2019 and 2022.
  • The prevalence of atypical CL was found to be 12.1%, with common atypical lesions including lupoid, erysipeloid, and impetiginous types, along with many others resembling various skin conditions and diseases.
  • The research highlights that CL can mimic a wide range of infectious, inflammatory, and neoplastic disorders, stressing the importance of thorough differential diagnosis for persistent non-healing skin lesions, especially in areas where CL is
View Article and Find Full Text PDF

Juvenile gangrenous vasculitis is characterized by the abrupt onset of scrotal ulcerations in young males, preceded by fever and pharyngeal symptoms. The etiology of this disease is poorly understood. The course is benign and self-limiting within a few weeks with no relapse.

View Article and Find Full Text PDF

Neutral theory: applicability and neutrality of clinical study endpoints where a disease-specific instrument is available.

BMC Med Res Methodol

May 2023

Medialis Ltd, 3 Warren Yard, Wolverton Mill, Milton Keynes, MK12 5NW, UK.

Background: There is a pressing need to improve the accuracy of rare disease clinical study endpoints. Neutral theory, first described here, can be used to assess the accuracy of endpoints and improve their selection in rare disease clinical studies, reducing the risk of patient misclassification.

Methods: Neutral theory was used to assess the accuracy of rare disease clinical study endpoints and the resulting probability of false positive and false negative classifications at different disease prevalence rates.

View Article and Find Full Text PDF

Objectives: This study aims to examine the frequency and clinical association of lupus-related vasculitis in patients with systemic lupus erythematosus (SLE).

Patients And Methods: We retrospectively analyzed medical records of a total of 565 SLE patients (42 males, 523 females; mean age: 32.7±9.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!