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Soft nanotechnology: the potential of polyelectrolyte multilayers against E. coli adhesion to surfaces. | LitMetric

Soft nanotechnology: the potential of polyelectrolyte multilayers against E. coli adhesion to surfaces.

Arh Hig Rada Toksikol

Division of Physical Chemistry, Department of Chemistry, Faculty of Science, University of Zagreb, Zagreb, Croatia.

Published: March 2020

Preventing bacterial attachment to surfaces is the most efficient approach to controlling biofilm proliferation. The aim of this study was to compare anti-adhesion potentials of 5 and 50 mmol/L polyelectrolyte multilayers of poly(allylamine hydrochloride)/poly(sodium 4-styrenesulfonate), poly(4-vinyl-N-ethylpyridinium bromide)/ poly(sodium 4-styrenesulfonate), and poly(4-vinyl-N-isobutylpyridinium bromide)/poly(sodium 4-styrenesulfonate) against Escherichia coli. Glass surface was covered with five polyelectrolyte layers and exposed to bacterial suspensions. Poly(4-vinyl-N-ethylpyridinium bromide)/poly(sodium 4-styrenesulfonate) was the most effective against bacterial adhesion, having reduced it by 60 %, followed by poly(4-vinyl-N-isobutylpyridinium bromide)/poly(sodium 4- styrenesulfonate) (47 %), and poly(allylamine hydrochloride)/poly(sodium 4-styrenesulfonate) (38 %). Polyelectrolyte multilayers with quaternary amine groups have a significant anti-adhesion potential and could find their place in coatings for food, pharmaceutical, and medical industry.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837241PMC
http://dx.doi.org/10.2478/aiht-2020-71-3319DOI Listing

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