Cochlear turns measurements in patients with meningitis: A histopathological study.

Laryngoscope Investig Otolaryngol

Department of Ophthalmology, Otolaryngology and Head and Neck Surgery Ribeirão Preto Faculty of Medicine (FMRP-USP) Ribeirão Preto São Paulo Brazil.

Published: June 2020

AI Article Synopsis

  • The study aimed to investigate changes in the cochlear turns area in patients who had meningitis by examining otopathologic samples.
  • Researchers analyzed the bony cochlear turns and lumen from temporal bones of meningitis patients and compared them to a healthy control group.
  • Findings revealed that meningitis patients had significantly reduced cochlear turn areas, especially in those who survived longer than 30 days post-diagnosis, suggesting a need for future research into the relationship between these changes and hearing outcomes.

Article Abstract

Objective: To demonstrate the cochlear turns area changes among patients with a history of meningitis, through otopatologic study.

Methods: We performed an analysis of the area of the bony cochlear turns and the cochlear lumen of the horizontal sections containing the modiolus and the area of the basal turn at the level of round window, in temporal bones obtained from patients with a history of meningitis and compared to a nondiseased control group.

Results: The mean area of the bony walls and the lumen of all cochlear turns are reduced within the meningitis group. Patients who presented a time from the diagnosis of meningitis to death longer than 30 days had a significant reduction in the cochlear turns area, as compared to the control group.

Conclusion: Future studies may further correlate audiologic outcomes, cochlear volume, and cochlear area among patients with meningitis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314461PMC
http://dx.doi.org/10.1002/lio2.383DOI Listing

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