Objective: Improving the quality of prescribing in the elderly remains a permanent concern and a major opportunity to improve patient care. The objective of this article is to propose, from updated existing lists of potentially inappropriate medication (PIM), a list of PIM adapted to the French medical practice.
Method: Combination of an explicit tool: the updated EU (7) PIM list published in 2015, adapted to the French medical practice (availability of drugs and validated indications), and an implicit tool: the recommendations of French National Health Authority (HAS) and more specifically the "alerte et maîtrise de la iatrogénie" (AMI) tools.
Results: From 289 PIM identified in the EU(7) PIM list, 183 drugs were included in our list according to our method. Three PIM were added to the list of "questionable" PIMs in accordance with the new French recommendations. A total of 90 PIMs were removed because of their indications or their non-commercialization in France.
Conclusion: This work provides an adaptation of the EU(7)PIM to the French medical practice with the guidance of the HAS recommendations. This list is intended to be easy to use for the identification of PIMs by French physicians.
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http://dx.doi.org/10.1016/j.therap.2020.06.001 | DOI Listing |
J Particip Med
January 2025
Department of Ambulatory Care, Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.
Background: Health authorities worldwide have invested in digital technologies to establish robust information exchange systems for improving the safety and efficiency of medication management. Nevertheless, inaccurate medication lists and information gaps are common, particularly during care transitions, leading to avoidable harm, inefficiencies, and increased costs. Besides fragmented health care processes, the inconsistent incorporation of patient-driven changes contributes to these problems.
View Article and Find Full Text PDFAnn Intensive Care
January 2025
Department of Anesthesiology, Critical Care, and Surgery, Duke University School of Medicine, Durham, NC, USA.
Front Oncol
January 2025
The Second Department of General Surgery, the Fourth Hospital of Hebei Medical University, Hebei, Shijiazhuang, China.
Background: Stromal-cell-derived factor 1 (SDF-1) plays a crucial role in hematopoiesis and has been implicated in acute myeloid leukemia (AML) pathogenesis. Understanding its relationship with chemotherapy outcomes could lead to improved therapeutic approaches for elderly AML patients.
Methods: This study retrospectively analyzed the medical records of elderly AML patients (n = 187) and compared serum SDF-1α levels with age-matched controls (n = 120).
Palliat Care Soc Pract
January 2025
Faculté des Sciences Infirmières, Université Laval, Québec, QC, Canada.
Background: Informed end-of-life decision-making requires a high level of death literacy. We still know little about the general population's level of knowledge and its determinants.
Aim: To assess knowledge of the general population regarding the legal status and definitions of various end-of-life practices, and to compare the level of knowledge according to individual characteristics known to influence death literacy.
Pediatr Rheumatol Online J
January 2025
Aga Khan University Medical College East Africa, Nairobi, Kenya.
Background: There are limited studies of juvenile dermatomyositis (JDM) in low and middle-income countries (LMIC). Many demonstrate delays to care, high prevalence of severe manifestations, and high mortality. Given the disease-associated damage with JDM, understanding JDM in Africa further is critical.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!