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| http://dx.doi.org/10.1002/jmv.26228 | DOI Listing |
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Revealing the role of natural killer cells in ankylosing spondylitis: identifying diagnostic biomarkers and therapeutic targets.
Ann Med
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Department of Rheumatology and Immunology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong Province, People's Republic of China.
Background: Ankylosing spondylitis (AS) is a chronic autoimmune disease that primarily affects the axial joints. Immune cells play a key role in the pathogenesis of AS. This study integrated bioinformatics methods with experimental validation to explore the role of natural killer (NK) cells in AS.
View Article and Find Full Text PDFReflections on COVID-19: A Literature Review of SARS-CoV-2 Testing.
Vaccines (Basel)
December 2024
Department of Laboratory Medicine, Changi General Hospital, 2 Simei Street 3, Singapore 529889, Singapore.
Although the Coronavirus disease 2019 (COVID-19) pandemic has ended, there are still many important lessons we can learn, as the pandemic profoundly affected every area of laboratory practice. During the pandemic, extensive changes to laboratory staffing had to be implemented, as many healthcare institutions required regular screening of all healthcare staff. Several studies examined the effectiveness of different screening regimens and concluded that repeated testing, even with lower sensitivity tests, could rival the performance of gold-standard RT-PCR testing in the detection of new cases.
View Article and Find Full Text PDFThe relationship between HYDIN and fallopian tubal cilia loss in patients with epithelial ovarian cancer.
Front Oncol
January 2025
Department of Pathology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Introduction: Primary cilia play an important role in the development of cancer by regulating signaling pathways. Several studies have demonstrated that women with mutations have, on average, 50% fewer ciliated cells compared with general women. However, the role of tubal cilia loss in the development of epithelial ovarian cancer (EOC) remains unclear.
View Article and Find Full Text PDFACCREDIT: Validation of clinical score for progression of COVID-19 while hospitalized.
Glob Epidemiol
June 2025
Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Brazil.
Unlabelled: COVID-19 is no longer a global health emergency, but it remains challenging to predict its prognosis.
Objective: To develop and validate an instrument to predict COVID-19 progression for critically ill hospitalized patients in a Brazilian population.
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Imperatorin's Effect on Myocardial Infarction Based on Network Pharmacology and Molecular Docking.
Cardiovasc Ther
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Department of Cardiology, The Fourth Affiliated Hospital, Nanjing Medical University, Nanjing, China.
Myocardial infarction (MI), a severe cardiovascular disease, is the result of insufficient blood supply to the myocardium. Despite the improvements of conventional therapies, new approaches are needed to improve the outcome post-MI. Imperatorin is a natural compound with multiple pharmacological properties and potential cardioprotective effects.
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