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| http://dx.doi.org/10.1016/j.anpedi.2020.06.002 | DOI Listing |
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Evolution of incidence of chilblain-like lesions in children during the first year of COVID-19 pandemic.
Pediatr Dermatol
March 2022
Department of Dermatology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.
Background: The COVID-19 pandemic has brought innumerable reports of chilblains. The relation between pernio-like acral eruptions and COVID-19 has not been fully elucidated because most reported cases have occurred in patients with negative microbiological tests for SARS-CoV-2.
Methods: A retrospective study of 49 cases of chilblains seen during the first year of the pandemic in a children's hospital in Madrid, Spain.
Chilblains during lockdown are associated with household exposure to SARS-CoV-2: a multicentre case-control study.
Clin Microbiol Infect
February 2022
EA 7449 REPERES (Pharmacoepidemiology and Health Services Research), Rennes 1 University, Rennes, France; Department of Dermatology, CHU Rennes, Rennes, France. Electronic address:
Objectives: During the COVID-19 pandemic, numerous cases of chilblains have been reported. However, in most cases, RT-PCR or serology did not confirm SARS-CoV-2 infection. Hypotheses have been raised about an interferon-mediated immunological response to SARS-CoV-2, leading to effective clearance of the SARS-CoV-2 without the involvement of humoral immunity.
View Article and Find Full Text PDFInflammatory Skin Lesions in Three SARS-CoV-2 Swab-Negative Adolescents: A Possible COVID-19 Sneaky Manifestation?
Pediatr Rep
April 2021
Pediatric Dermatology, University of Bari Aldo Moro, 11, 70124 Bari, Italy.
Coronavirus disease 19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is associated with various clinical manifestations, including skin lesions. In particular, during the COVID-19 pandemic lock-down period numerous chilblain-like lesions, mainly located on the feet, were observed in adolescents. The latter were often asymptomatic or associated with very mild respiratory symptoms.
View Article and Find Full Text PDFThe Influence of Media Coverage and Governmental Policies on Google Queries Related to COVID-19 Cutaneous Symptoms: Infodemiology Study.
JMIR Public Health Surveill
February 2021
Assistance Publique des Hôpitaux de Paris (AP-HP), Département de dermatologie, Hôpital Henri Mondor, Créteil, France.
Background: During COVID-19, studies have reported the appearance of internet searches for disease symptoms before their validation by the World Health Organization. This suggested that monitoring of these searches with tools including Google Trends may help monitor the pandemic itself. In Europe and North America, dermatologists reported an unexpected outbreak of cutaneous acral lesions (eg, chilblain-like lesions) in April 2020.
View Article and Find Full Text PDFCOVID toes: where do we stand with the current evidence?
Int J Infect Dis
January 2021
Department of Dermatology, Cliniques universitaires Saint-Luc, Université catholique de Louvain (UCLouvain), Avenue Hippocrate 10, 1200, Brussels, Belgium. Electronic address:
Background: Numerous of cases of chilblains have been observed, mainly in young subjects with no or mild symptoms compatible with COVID-19. The pathophysiology of these lesions is still widely debated and an association with SARS-CoV-2 infection remains unconfirmed.
Objectives: This paper focus on the unresolved issues about these COVID toes and in particular whether or not they are associated with COVID-19.
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