Formulation of anti-acne concealer containing cinnamon oil with antimicrobial activity against .

J Adv Pharm Technol Res

Department of Pharmaceutical Technology, Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok 65000, Thailand.

Published: April 2020

This study aimed to develop an anti-acne concealer containing essential oil with anti- activity. Antimicrobial activity of cinnamon oil, galangal oil, and eucalyptus oil against DMST 14916 was assayed using agar disc diffusion and the broth dilution method. Cinnamon oil showed the maximum inhibitory activity against with a clear zone diameter of 36.75 ± 1.06 mm, compared to 14.67 ± 0.58 and 41.83 ± 1.04 mm for tea tree oil and clindamycin, respectively. The minimum inhibitory concentration value of cinnamon oil was 5 mg/mL. Among five formulations of concealer incorporating 0.5% w/w cinnamon oil, F4 provided good texture, coverage, and spreadability with anti- activity and stable under determined storage conditions. Cinnamon oil could be a promising cosmetic ingredient for anti-acne products, and F4 concealer may be useful for both covering skin imperfections and the management of acne.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305778PMC
http://dx.doi.org/10.4103/japtr.JAPTR_1_20DOI Listing

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