AI Article Synopsis
- An 8-year-old male neutered domestic shorthair cat was diagnosed with pancreatic adenocarcinoma and treated through surgical resection and toceranib phosphate.
- The cat experienced a remarkable progression-free interval of 1148 days and lived for over 1436 days post-treatment.
- This case marks the first documentation of coat hypopigmentation as a side effect of toceranib in cats, although it has been noted in dogs.
Article Abstract
Case Summary: Primary pancreatic adenocarcinoma is an uncommon neoplasm seen in cats and often has a poor prognosis. We report a case of an 8-year-old male neutered domestic shorthair cat weighing 5.8 kg diagnosed with pancreatic adenocarcinoma treated with surgical resection and toceranib phosphate, which had a progression-free interval of 1148 days and survived for more than 1436 days. The treatment was well tolerated; however, the cat developed generalised coat hypopigmentation.
Relevance And Novel Information: To our knowledge, the cat in our report has the longest progression-free interval and survival time post-surgical resection of pancreatic carcinoma treated with toceranib. Hypopigmentation as a side effect of toceranib has been reported in dogs, but this is the first case reported in cats.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294497 | PMC |
| http://dx.doi.org/10.1177/2055116920924911 | DOI Listing |
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