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Hemodynamics and vascular oxygenation measured at the forehead during changes in respiration: A SPA-fNIRS study.

Respir Physiol Neurobiol

January 2025

Biomedical Optics Research Laboratory, Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Neuroscience Center Zurich, University of Zurich and ETH Zurich, Zurich, Switzerland.

Significance: Cerebral blood flow is influenced by respiration, primarily through changes in the CO concentration of arterial blood.

Aim: The objective of this study was to investigate the effect of changes in arterial CO concentration induced by respiratory changes on oxygenation and hemodynamics in the cerebral and extracerebral tissue layers of the forehead.

Approach: We used systemic physiology augmented functional near-infrared spectroscopy (SPA-fNIRS) to assess changes in forehead hemodynamics and oxygenation as well as systemic physiology in 20 healthy subjects.

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  • The study investigated how different breathing frequencies in yoga (high-frequency vs. low-frequency) impact mood, attention, and other mental states.
  • Thirty young adults participated, with one group practicing high-frequency breathing and the other low-frequency breathing on different days, while various physiological and psychological measures were recorded.
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