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http://dx.doi.org/10.1183/13993003.00162-2020 | DOI Listing |
Respir Physiol Neurobiol
January 2025
Biomedical Optics Research Laboratory, Department of Neonatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Neuroscience Center Zurich, University of Zurich and ETH Zurich, Zurich, Switzerland.
Significance: Cerebral blood flow is influenced by respiration, primarily through changes in the CO concentration of arterial blood.
Aim: The objective of this study was to investigate the effect of changes in arterial CO concentration induced by respiratory changes on oxygenation and hemodynamics in the cerebral and extracerebral tissue layers of the forehead.
Approach: We used systemic physiology augmented functional near-infrared spectroscopy (SPA-fNIRS) to assess changes in forehead hemodynamics and oxygenation as well as systemic physiology in 20 healthy subjects.
Int J Yoga
September 2024
Department of Yoga Science, University of Patanjali, Haridwar, Uttarakhand, India.
J Hypertens
September 2024
Department of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, Leiden.
Purpose: We studied the relative contributions of total peripheral resistance (TPR), stroke volume (SV) and heart rate (HR) to low blood pressure in classical orthostatic hypotension (cOH) on group and individual levels.
Methods: We retrospectively analyzed tilt test records from cOH patients and age/sex-matched controls. We quantified relative effects of HR, SV and TPR on mean arterial pressure (MAP) with the log-ratio method.
Sci Rep
September 2024
Department of Teacher Education, NLA University College, Oslo, Norway.
J Appl Physiol (1985)
November 2024
Exercise Physiology Research Group, Department of Movement Sciences, KU Leuven, Leuven, Belgium.
Acute mountain sickness (AMS) represents a considerable issue for individuals sojourning to high altitudes with systemic hypoxemia known to be intimately involved in its development. Based on recent evidence that ketone ester (KE) intake attenuates hypoxemia, we investigated whether exogenous ketosis might mitigate AMS development and identified underlying physiological mechanisms. Fourteen healthy, male participants were enrolled in two 29-h protocols (simulated altitude of 4,000-4,500 m) receiving either KE or a placebo (CON) at regular timepoints throughout the protocol in a randomized, crossover manner.
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