Objective: To evaluate the effect of NaOCl irrigant activation using passive ultrasonic activation, F-files, XP-endo Finisher files and or needle irrigation alone on the reduction of intracanal bacteria from root canals in teeth undergoing root canal treatment.
Methods: Eighty patients with asymptomatic apical periodontitis were randomly divided into four groups. Access cavities were prepared and pre-treatment samples were taken (S1). Canals were then prepared and post-instrumentation samples (S2) taken. NaOCl was then activated with the various irrigant activation systems and post-irrigation samples (S3) taken. The samples were processed and colony forming units (CFUs) of bacteria were determined. The reduction in CFUs among the experimental groups were analysed using the Kruskal Wallis test and pairwise comparisons with the Mann-Whitney test. The Friedman test was used to compare the differences in the reduction of CFUs within the groups.
Results: Overall, for all groups there was a significant reduction in the CFUs from S1 to S2 (P < 0.05) and from S2 to S3 (P < 0.05). Both XP-endo Finisher and passive ultrasonic activation techniques were associated with the greatest reduction in CFUs with no significant difference between them (P = 0.24). However, both were associated with significantly lower CFUs when compared to F-file activation and needle irrigation (P < 0.05). F-file activation reduced the CFUs significantly more compared to needle irrigation (P = 0.04).
Conclusions: XP-endo Finisher file activation and passive ultrasonic activation were equivalent in terms of reduction in CFUs. F-file activation did not reduce the CFUs to the same extent as the XP-endo Finisher file and ultrasonic activation but reduced the CFUs more than needle irrigation.
Clinical Significance: The present study highlights the effect of new XP-endo Finisher file and passive ultrasonic activation in reducing the bacterial load from the root canal system which is important for the success of root canal treatment.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jdent.2020.103412 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The disinfectant effects of portable ultraviolet light devices and their application to dentures.
Photodiagnosis Photodyn Ther
December 2024
Department of Fixed Prosthodontics and Orofacial Function, Graduate School of Dentistry, Osaka University, Suita, Japan.
Interest in ultraviolet (UV) light devices for disinfection has increased due to pandemic concerns, but their efficacy in denture disinfection is underexplored. This study evaluated seven-enclosed type portable UV irradiation devices (devices A-G). Among these, devices A, B, and C used bulb light sources, while devices D, E, F, and G utilized LED (light-emitting diode) light sources.
View Article and Find Full Text PDFEfficacy of UV-C 254 nm Light and a Sporicidal Surface Disinfectant in Inactivating Spores from Ribotypes In Vitro.
Pathogens
November 2024
Department of Microbiology-Biotechnology, Faculty of Technology, University of Applied Sciences Emden/Leer, 26723 Emden, Germany.
is widely recognised as one of the most common causes of healthcare-associated infections due to the ability of spores to survive for prolonged periods in the hospital environment. This study aimed to evaluate the efficacy of UV-C 254 nm light in the inactivation of the spores of different ribotypes on brain heart infusion (BHI) agar plates or in phosphate-buffered saline (PBS) with varying spore densities. Furthermore, the effectiveness of a sporicidal surface disinfectant against spores was determined on different surfaces.
View Article and Find Full Text PDFMechanistic Insight into the Anti-Bacterial/Anti-Biofilm Effects of Low Chlorhexidine Concentrations on -In Vitro Study.
Microorganisms
November 2024
Biofilm Research Laboratory, The Institute of Biomedical and Oral Research (IBOR), The Faculty of Dental Medicine, The Hebrew University of Jerusalem, Jerusalem 9112102, Israel.
Background: Endodontic treatment failures are often linked to the persistence of in the root canal system. This study aimed to investigate the antibacterial/antibiofilm mechanism of chlorhexidine (CHX), particularly at low concentrations, against , to improve endodontic treatment protocols.
Methods: The antibacterial activity of CHX (0.
Investigating the Antibacterial Ability of Sodium Hypochlorite Solution Activated with PUI and XPF File Against Using CFU, RT-PCR, and SEM.
Bioengineering (Basel)
October 2024
Department of Human Genetics, School of Dental Medicine, University of Belgrade, 11000 Beograd, Serbia.
Article Synopsis
In (Mtb), persisters are genotypically drug-sensitive bacteria that nonetheless survive antibiotic treatment. Persisters represent a significant challenge to shortening TB treatment and preventing relapse, underscoring the need for new therapeutic strategies. In this study, we screened 2,336 FDA-approved compounds to identify agents that enhance the sterilizing activity of standard anti-TB drugs and prevent the regrowth of persisters.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!