Herein, we report a protocol for visible-light-induced dearomative oxamination reactions of indole derivatives to afford functionalized spirocyclic products. These step-economical reactions, which involve C-N and C-O bond formation, feature mild conditions, a broad substrate scope, high yields, exclusive diastereoselectivity and step-economy. In addition, a similar protocol could be used to synthesize spirolactams by dearomative amidation of phenol derivatives.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d0cc03506h | DOI Listing |
Publication Analysis
Top Keywords
visible-light-induced dearomative
8
dearomative oxamination
8
indole derivatives
8
dearomative amidation
8
amidation phenol
8
phenol derivatives
8
oxamination indole
4
derivatives
4
derivatives dearomative
4
derivatives report
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!