Containment strategies and clinical management of coronavirus disease (COVID-19) patients during the current pandemic depend on reliable diagnostic PCR assays for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we compare 11 different RT-PCR test systems used in seven diagnostic laboratories in Germany in March 2020. While most assays performed well, we identified detection problems in a commonly used assay that may have resulted in false-negative test results during the first weeks of the pandemic.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315722 | PMC |
| http://dx.doi.org/10.2807/1560-7917.ES.2020.25.24.2001057 | DOI Listing |
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