The objective of this study was to estimate the concentrations of indoor air pollutants in unregulated public transport means in Korea and to determine the factors affecting the air quality as well as to assess the harmful effects of indoor air pollutants on the health of passengers. The correlation between particulate matter (PM) and number of passengers on intra-city buses, express buses, town shuttle buses, or rural buses was insignificant whether it was during rush hours or non-rush hours. In regard to PM on express buses, there was no case where the standard limit was exceeded during the winter and summer seasons. In winter, however, the average concentration of PM10 increased by the travel distance. In regard to CO, there was a statistically significant correlation (p < 0.05) between CO concentrations and the number of passengers, owing to human respiration. Unlike the case of PM, there was a difference between rush hours and non-rush hours. Regarding volatile organic compounds (VOCs) and aldehydes, the values were high among recently manufactured vehicles regardless of bus types. The standard limit was exceeded during the summer season, which seemed to be related to the temperature and humidity in both indoor and outdoor. The results of this study indicate that the excess mortality resulting from PM was as high as the safety margin during both non-rush hours and rush hours among all unregulated public transportation means. The excess cancer risk and non-cancer risk of VOCs and aldehydes were as high as the safety margin during both non-rush hours and rush hours.
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http://dx.doi.org/10.1007/s11356-020-09792-z | DOI Listing |
Anal Chem
January 2025
School of Chemistry and Chemical Engineering, Anhui University of Technology, Ma'anshan 243032, P. R. China.
Ulcerative colitis (UC), often referred to as "green cancer", is a chronic inflammatory bowel disease with an unclear etiology, closely associated with the imbalance of hydrogen sulfide (HS) and peroxynitrite (ONOO). HS exhibits anti-inflammatory effects at physiological levels, but excessive concentrations can compromise the intestinal barrier, while ONOO aggravates inflammation. To facilitate the molecular-level monitoring of these compounds in UC, we developed a novel fluorescent probe, , capable of simultaneously detecting HS and ONOO via distinct fluorescent channels in a cascade mode.
View Article and Find Full Text PDFBMC Public Health
January 2025
Department of Ophthalmology, Guangdong Eye Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, 106 Zhongshan Er Road, Guangzhou, 510080, Guangdong, PR China.
Background: Traffic-related air pollution especially in highly socioeconomically developed megacity is usually considered as a severe problem leading to inevitable adverse health outcomes. This study aimed to investigate the associations between traffic-related air pollutants with risk of dry eye disease (DED) outpatient visits in a megacity (Guangzhou) along the subtropical coast in South China.
Methods: Daily data on DED outpatient visits and environmental variables from 1 January 2014 to 31 December 2020 in Guangzhou were obtained.
Environ Pollut
January 2025
Cancer Research Center, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China; Department of Medical Oncology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China. Electronic address:
Air pollution is a well-established risk factor for lung cancer, but limited evidence exists on its impact on the treatment of lung cancer. The objective of this study was to investigate the impact of key pollutants on the efficacy of PD-1/PD-L1 inhibitor immunotherapy in non-small cell lung cancer (NSCLC) patients, thereby providing clinicians with evidence to potentially enhance the efficacy of PD-1 therapy and inform policy decisions for cancer care. To this end, we conducted a study involving 361 NSCLC patients who received PD-1/PD-L1 inhibitor immunotherapy, examining the correlation between air pollution exposure and progression-free survival (PFS) following immunotherapy treatment.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Department of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA 02114.
Radon, a common radioactive indoor air pollutant, is the second leading cause of lung cancer in the United States. Knowledge about its distribution is essential for risk assessment and designing efficient protective regulations. However, the three current radon maps for the United States are unable to provide the up-to-date, high-resolution, and time-varying radon concentrations.
View Article and Find Full Text PDFInt J Biometeorol
January 2025
Department of Preventive Health, Shanxi Cardiovascular Hospital, No. 18 Yifen Street, Wanbailin District, Taiyuan, 030024, Shanxi Province, China.
Air pollution remains a significant threat to human health and economic development. Most previous studies have examined the health effects of individual pollutants, which often overlook the combined impacts of multiple pollutants. The traditional composite indicator air quality index (AQI) only focuses on the major pollutants, whereas the health risk-based air quality index (HAQI) could offer a more comprehensive evaluation of the health effects of various pollutants on populations.
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