We study a linear Langevin dynamics driven by an additive non-Markovian symmetrical dichotomic noise. It is shown that when the statistics of the time intervals between noise transitions is characterized by two well differentiated timescales, the stationary distribution may develop multimodality (bi- and trimodality). The underlying effects that lead to a probability concentration in different points include intermittence and also a dynamical locking of realizations. Our results are supported by numerical simulations as well as by an exact treatment obtained from a Markovian embedding of the full dynamics, which leads to a third-order differential equation for the stationary distribution.
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http://dx.doi.org/10.1103/PhysRevE.101.052137 | DOI Listing |
J Clin Exp Dent
November 2024
DDS, MS, PhD. Post-Graduate Program in Dentistry (Prosthodontics), Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.
Background: Sleep bruxism is a major research area in dentistry today and needs valid clinical means of diagnosis against valid instrumental methods. Purpose: To assess the validity of the most commonly reported sleep bruxism (SB) signs and symptoms in the literature against a polysomnography (PSG) validated portable electromyographic (EMG) device (BiteStrip®).
Material And Methods: Fifty young adults (40 women & 10 men, 18-30 years old) volunteered for the sequential and simultaneous administration of the SB signs and symptoms questionnaire versus the BiteStrip®.
Diagnosis (Berl)
December 2024
Department of Medicine, Division of Respiratory & Critical Care Medicine, 59053 National University Hospital, Singapore.
J Clin Epidemiol
November 2024
School of Population Health, The University of Queensland, Brisbane, Queensland, Australia.
Background And Objectives: Programmed-death-1/ligand-1 inhibitors (PD-1/L1is) have emerged as pivotal treatments for many cancers. A notable feature of this class of medicines is the dichotomous response pattern: A small (but clinically relevant) percentage of patients (5%-20%) benefit from deep and durable responses resembling functional cures (durable responders), while most patients experience only a modest or negligible response. Accurately predicting durable responders remains elusive due to the lack of a reliable biomarker.
View Article and Find Full Text PDFJ Am Acad Audiol
October 2022
Department of Biostatistics, Collaborative Studies Coordinating Center, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Background: Individual cardiovascular disease (CVD) risk factors (RFs) have been associated with hearing loss (HL). The relationship to aggregate risk is poorly understood and has not been explored in the Hispanic/Latino population.
Purpose: The aim of this study was to characterize the association between aggregate CVD RF burden and hearing among Hispanics/Latinos.
Int J Hyg Environ Health
January 2025
Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA.
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