Bioactivity-guided isolation of the CHCl-soluble fraction of the roots of was carried out to obtain a new cardenolide glycoside, caloside G. Its absolute structure was elucidated based on NMR and ECD spectroscopic data interpretation. Caloside G showed noteworthy cytotoxicity against the PANC-1 human pancreatic and HeLa human cervical carcinoma cell lines, with the submicromolar IC values of 0.038 and 0.09 M, respectively.
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| http://dx.doi.org/10.1080/14786419.2020.1781114 | DOI Listing |
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