Introduction: Prevalence of overweight and obesity are increas- ing in the last decades, and with them, diseases and health conditions such as diabetes, hypertension or cardiovascular diseases. However, hos- pital databases usually do not record such conditions in adults, neither anthropomorfic measures that facilitate their identification.

Methods: We implemented a machine learning method based on PU (Positive and Unlabelled) Learning to identify obese patients without a diagnose code of obesity in the health records.

Results: The algorithm presented a high sensitivity (98%) and predicted that around 18% of the patients without a diagnosis were obese. This result is consistent with the report of the WHO.

Download full-text PDF

Source
http://dx.doi.org/10.3233/SHTI200284DOI Listing

Publication Analysis

Top Keywords

positive unlabelled
8
machine learning-based
4
learning-based identification
4
identification obesity
4
obesity positive
4
unlabelled electronic
4
electronic health
4
health records
4
records introduction
4
introduction prevalence
4

Similar Publications

Preclinical Study of a Dual-Target Molecular Probe Labeled with Ga Targeting SSTR2 and FAP.

Pharmaceuticals (Basel)

December 2024

Department of Nuclear Medicine, First Medical Center, Chinese PLA General Hospital, Fuxing Road 28, Beijing 100853, China.

Objective: Currently, Ga-labeled somatostatin analogs (SSAs) are the most commonly used imaging agents for patients with neuroendocrine tumors (NETs) in clinical practice, demonstrating good results in tumor diagnosis. For applications in peptide receptor radionuclide therapy (PRRT), targeted drugs should have high tumor uptake and prolonged tumor retention time. To enhance the uptake and retention of tracers in NETs, our goal is to design a Ga-labeled heterodimer for optimizing pharmacokinetics and assess whether this form is more efficacious than its monomeric equivalents.

View Article and Find Full Text PDF

Vector-borne diseases pose a major worldwide health concern, impacting more than 1 billion people globally. Among various blood-feeding arthropods, mosquitoes stand out as the primary carriers of diseases significant in both medical and veterinary fields. Hence, comprehending their distinct role fulfilled by different mosquito types is crucial for efficiently addressing and enhancing control measures against mosquito-transmitted diseases.

View Article and Find Full Text PDF

AI-directed formulation strategy design initiates rational drug development.

J Control Release

December 2024

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences (ICMS), University of Macau, Macau, China; Department of Public Health and Medicinal Administration, Faculty of Health Sciences (FHS), University of Macau, Macau, China. Electronic address:

Rational drug development would be impossible without selecting the appropriate formulation route. However, pharmaceutical scientists often rely on limited personal experiences to perform trial-and-error tests on diverse formulation strategies. Such an inefficient screening manner not only wastes research investments but also threatens the safety of clinical volunteers and patients.

View Article and Find Full Text PDF

Objective: The paper aims to address the problem of massive unlabeled patients in electronic health records (EHR) who potentially have undiagnosed diabetic retinopathy (DR). It is desired to estimate the actual DR prevalence in EHR with 96 % missing labels.

Materials And Methods: The Cerner Health Facts data are used in the study, with 3749 labeled DR patients and 97,876 unlabeled diabetic patients.

View Article and Find Full Text PDF

Semi-supervised medical image segmentation endeavors to exploit a limited set of labeled data in conjunction with a substantial corpus of unlabeled data, with the aim of training models that can match or even exceed the efficacy of fully supervised segmentation models. Despite the potential of this approach, most existing semi-supervised medical image segmentation techniques that employ consistency regularization predominantly focus on spatial consistency at the image level, often neglecting the crucial role of feature-level channel information. To address this limitation, we propose an innovative method that integrates graph convolutional networks with a consistency regularization framework to develop a dynamic graph consistency approach.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!