AI Article Synopsis
- A new method to create a titanium coating (ZnO@ZnS nanorod-array) enhances cell-selectivity, promoting healthy cell functions while fighting bacterial invasion.
- The coating allows for controlled release of zinc, which optimally decreases from 3.5 mg/L to 0.3 mg/L within the first week, improving interaction with gingival fibroblasts (HGnFs).
- This technique shows 100% antibacterial effectiveness against common bacteria (S. aureus and E. coli), suggesting it can improve soft tissue sealing and reduce peri-implantitis in dental implants.
Article Abstract
Cell-selective toxic titanium is highly desired in clinical dental practice. Herein, based on the in situ conversion of ZnO to ZnO@ZnS, nanorod-array structured coatings with a controllable release features of zinc (Zn), has been successfully fabricated by a two-step hydrothermal method to endow titanium surface with cell-selectivity, i.e. boosting the functions (attachment and migration) of human gingival fibroblasts (HGnFs) while acting against the invasion of pathogenic bacteria. The improved functions of HGnFs over the ZnO@ZnS nanorod-array were attributed to the material's optimized zinc release, which was decreased from an order of 3.5 mg L to about 0.3 mg L (within the first week). But more importantly, this concentration still had a high antibacterial efficacy up to 100% (against both the S. aureus and E. coli, 10 CFU mL). This study demonstrated that a ZnO@ZnS nanorod-array coating could be a promising strategy to endow titanium dental implants with improved soft tissue sealing and effectively reduce peri-implantitis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jcis.2020.06.055 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!