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Androgens induce renal synthesis of urinary lipocalin-family protein, a potential inter-sexual transmitter in viviparous rockfish.
Biochim Biophys Acta Gen Subj
January 2025
Division of Marine Life Science, Faculty of Fisheries Sciences, Hokkaido University, 3-1-1 Minato, Hakodate, Hokkaido 041-8611, Japan. Electronic address:
In viviparous black rockfish (Sebastes schlegelii), the kidney of reproductive-phase males actively produces lipocalin-type prostaglandin D synthase homolog (LPGDSh) protein, which is presumably involved in intersexual communication when emitted in the urine. The present study was undertaken to discover whether androgens and their nuclear receptors (Ars) are engaged in regulation of renal LPGDSh protein synthesis in black rockfish. Quantitative real-time polymerase chain reaction, in conjunction with immunohistochemistry and highly sensitive enzyme-linked immunosorbent assay, revealed that intra-abdominal administration of a synthetic androgen, 17α-methyltestosterone (MT), to juvenile black rockfish induced their renal expression of LPGDSh transcript and protein.
View Article and Find Full Text PDFUltrasound-guided vs. laparoscopic-guided transversus abdominis plane block for postoperative pain following laparoscopic cholecystectomy: a systematic review and meta-analysis.
Ir J Med Sci
January 2025
Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Article Synopsis
- Postoperative pain after laparoscopic cholecystectomy (LC) is significant, and the transversus abdominis plane block (TAPB) is a method to manage this pain, delivered via ultrasound (UTAPB) or laparoscopic (LTAPB) guidance.
- A systematic review of randomized studies indicated that UTAPB was more effective in reducing pain after 6 hours compared to LTAPB, while the difference in effectiveness diminished over time at 12, 24, and 48 hours.
- The study concludes that UTAPB provides better early pain relief after LC, suggesting that further research is necessary to confirm these findings.
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