AI Article Synopsis

  • Gastric smooth muscle neoplasms, like gastric leiomyosarcoma, are rare cancers that are not well-researched, making them tricky to diagnose compared to more common cancers like GIST.
  • They often have subtle symptoms and varied outcomes, which complicates their clinical management.
  • The case discussed involves a young woman who developed metastatic gastric leiomyosarcoma after being treated for acute lymphoblastic leukemia with chemoradiotherapy, suggesting a potential link between her previous cancer treatment and the development of this neoplasm.

Article Abstract

Gastric smooth muscle neoplasms are rare and poorly investigated malignancies. Their importance relies on differential diagnosis with more frequent neoplasms(e.g. GIST), on their often mild and deceitful clinical presentation and on their heterogeneous outcome. Moreover, the pathogenesis of gastric leiomyosarcoma seems to point to some acknowledged oncogenic factors such as radiations or oncogenic viral infections. Herein, we describe a case of metastatic gastric leiomyosarcoma in a young woman, previously diagnosed with acute lymphoblastic leukemia treated with chemoradiotherapy.

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Source
http://dx.doi.org/10.1016/j.clinre.2020.05.019DOI Listing

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