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| http://dx.doi.org/10.1111/odi.13496 | DOI Listing |
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Vaccination prior to SARS-CoV-2 infection does not affect the neurologic manifestations of long COVID.
Brain Commun
January 2025
Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Persistent symptoms after COVID-19 constitute the long COVID syndrome, also called post-acute sequelae of SARS-CoV-2 infection (PASC). COVID-19 vaccines reduce the gravity of ensuing SARS-CoV-2 infections. However, whether vaccines also have an impact on PASC remain unknown.
View Article and Find Full Text PDFMeta-analysis of the effect of non-pharmacological interventions on the development of dysgeusia in patients undergoing radiotherapy for head and neck squamous cell carcinoma.
Sci Rep
January 2025
Department of Oral Maxillofacial Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
This study was conducted by searching electronic databases from January 1, 2000 to August 8, 2023: Web of Science, PubMed, Cochrane Library, Embase, Scopus, Google Scholar, China Biomedical Literature Database (CBM), China National Knowledge Network (CNKI), China Science and Technology Journal Database (VIP) and Wan-fang Database were included in 14 studies with a total sample size of 1630 cases. This study conducted a meta-analysis of the literature published in recent years on the occurrence of dysgeusia in Head and neck squamous cell carcinoma (HNSCC) patients with non-pharmacological treatment, in order to provide the latest evidence-based evidence for medical staff and provide a basis for further intervention of dysgeusia in HNSCC patients. Compared with conventional care in the control group, In the experimental group, the non-pharmacological intervention reduced the score of dysgeusia [MD = - 0.
View Article and Find Full Text PDFA single-center, single-arm, prospective, open-label, and comparative trial to evaluate the safety and tolerability profile of a 90-day oral L-arginine hydrochloride intervention for patients with amyotrophic lateral sclerosis.
Sci Rep
January 2025
Department of Clinical Neuroscience and Therapeutics, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, Hiroshima, 734-8551, Japan.
Weight loss, a key indicator of malnutrition in amyotrophic lateral sclerosis (ALS) patients, negatively impacts patient prognosis. However, effective nutritional interventions have not been adequately established. Research in ALS model mice has shown that L-arginine can prolong survival; however, no human intervention studies have been conducted.
View Article and Find Full Text PDFAdverse Events Associated with Antivirals for COVID-19: An Analysis Based on FDA Adverse Event Reporting System (FAERS).
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Department of Pharmacy Practice and Clinical Pharmacy, Faculty of Pharmacy, Universiti Teknologi MARA (UiTM) Selangor Branch, 42300 Bandar Puncak Alam, Selangor, Malaysia.
Background: The COVID-19 pandemic has called for the rapid development and use of antiviral drugs to effectively control the disease. Nirmatrelvir/Ritonavir (Paxlovid), Molnupiravir, and Remdesivir have been pivotal in therapeutic approaches, although they raise concerns regarding adverse drug reactions (ADRs).
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Effect of a Steaming Treatment on the Alpha-Glucosidase Inhibitory Components in the Brown Alga .
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December 2024
Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology, 4-5-7 Konan, Tokyo 108-8477, Japan.
The brown alga (SF) is historically consumed as a food material in Japan. A steaming process is often required for SF products on the market due to their moderate hardness and astringent taste. This investigation aimed to elucidate the effect of steaming on the anti-diabetic activity of SF and its related chemical components.
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