Introduction: The objective of this study was to analyze which factors (including factors pertaining to the individual, the household, and the local area) increase the risk of fall injuries for the three age groups with the highest risk for fall injuries in Sweden.
Method: The study combined longitudinal data covering the period 1999-2013 from several different official registries from Statistics Sweden as well as from the Swedish health care system and fitted the models to data using mixed model regressions.
Results: Three age groups had a markedly heightened risk for fall injuries: 1-3-year olds, 12-14 year olds, and the elderly (65+). The home was the most common location for fall injuries, as about 40% of all fall injuries occur in the home. Only for the elderly strong predictors for fall injuries were found, and these were: age, single household, and special housing.
Conclusions: There is preventive potential in the special residences for the elderly and disabled. People living in these special residences make up a strongly selected group that needs extra safe environments. Our findings indicate that their needs are currently not meet. Practical applications: Design of special residences for the elderly and disabled should aim at reducing the consequences of falling.
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http://dx.doi.org/10.1016/j.jsr.2020.02.016 | DOI Listing |
Biochem Biophys Res Commun
January 2025
Cardiovascular Research Group, Department of Pharmacy, COMSATS University Islamabad, Abbottabad Campus, University Road, Tobe Camp, Abbottabad, 22060, KPK, Pakistan. Electronic address:
Gentisic acid (GA), a cytochrome P450 metabolite of the antiplatelet drug aspirin, exhibits smooth muscle relaxant, antiatherogenic, and antioxidant activities. It also has a protective role in hypertrophic heart failure, suggesting its role in the management of myocardial infarction (MI). This study aimed to explore the protective activity of GA in isoproterenol (ISO)-induced MI in Sprague-Dawley (SD) rats in-vivo, followed by mechanistic investigation ex-vivo.
View Article and Find Full Text PDFJ Cereb Blood Flow Metab
January 2025
Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK.
To what extent sildenafil, a selective inhibitor of the type-5 phosphodiesterase modulates systemic redox status and cerebrovascular function during acute exposure to hypoxia remains unknown. To address this, 12 healthy males (aged 24 ± 3 y) participated in a randomized, placebo-controlled crossover study involving exposure to both normoxia and acute (60 min) hypoxia (Fi = 0.14), followed by oral administration of 50 mg sildenafil and placebo (double-blinded).
View Article and Find Full Text PDFSensors (Basel)
January 2025
Advanced Institute of Convergence Technology, 145 Gwanggyo-ro, Yeongtong-gu, Suwon-si 16229, Gyeonggi-do, Republic of Korea.
According to South Korea's Ministry of Employment and Labor, approximately 25,000 construction workers suffered from various injuries between 2015 and 2019. Additionally, about 500 fatalities occur annually, and multiple studies are being conducted to prevent these accidents and quickly identify their occurrence to secure the golden time for the injured. Recently, AI-based video analysis systems for detecting safety accidents have been introduced.
View Article and Find Full Text PDFLife (Basel)
January 2025
Department of Surgery, Elmhurst Hospital Center, NYC Health + Hospitals/Elmhurst, 79-01 Broadway, Queens, NY 11373, USA.
Objectives: Subway-related accidents have risen with advancements in the system. We aim to study the injury patterns from these incidents.
Methods: This is a retrospective study from a single center, covering patients from 1 January 2016 to 31 December 2023.
Children (Basel)
December 2024
Department of Pediatrics, Division of Neonatology, University of Virginia, Charlottesville, VA 22908, USA.
Background/objectives: Motor deficits following neonatal brain injury, from cerebral palsy to subtle deficits in motor planning, are common yet underreported. Rodent models of motor deficits in neonatal hypoxia-ischemia (HI) allow improved understanding of the underlying mechanisms and neuroprotective strategies. Our goal was to test motor performance and learning in a mouse model of neonatal HI.
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