AI Article Synopsis
- Acute respiratory infections (ARIs) are a major public health issue globally, with viruses being key contributors; a study was conducted in southern China to analyze the prevalence and characteristics of these respiratory viruses over nearly a decade (2009-2018).
- Out of 22,680 respiratory samples collected from ARI patients, 43.03% tested positive for seven common viruses, with influenza being the most prevalent, followed by RSV and PIV, and notable differences in infection rates and types between genders and patient settings.
- The study highlights specific trends in virus circulation, indicating peak years for various viruses, and identifies co-detection rates, particularly noting that RSV, PIV, and Flu were the most frequently co-detected pathogens
Article Abstract
Background: Acute respiratory infections (ARIs) remain a significant public threat with high morbidity and mortality worldwide; viruses are significant pathogens that cause ARIs. This study was conducted to better understand the epidemiological characteristics of respiratory viruses circulating in southern China.
Methods: We collected 22,680 respiratory samples from ARI patients in 18 hospitals in southern China during 2009-2018; seven common respiratory viruses including Flu, RSV, PIV, hMPV, ADV, HCoV, and HBoV were screened using in-house real-time PCR.
Results: Of all samples, 9760 ARI cases (9760/22680, 43.03%) tested positive for the seven common respiratory viruses. The most detected virus was Flu (14.15%), followed by RSV (10.33%) and PIV (5.43%); Flu-A, PIV3, and HCoV-OC43 were the predominant subtypes. Although most of the viruses were detected in male inpatients, Flu was more likely detected in female outpatients. Flu infection was more likely to cause URTI (upper respiratory tract infection), whereas RSV infection was more likely to cause pneumonia and bronchitis. The prevalence of Flu was particularly high in 2009. The epidemic level was found notably high in 2014-2018 for RSV, in 2016-2018 for PIV, in the summer of 2018 for ADV, in the summer of 2016 and winter of 2018 for HCoV, and in the summer of 2011 and autumn of 2018 for HBoV. The co-detection rate of the seven viruses was 4.70%; RSV, PIV, and Flu were the most commonly co-detected viruses.
Conclusions: This work demonstrates the epidemiological characteristics of seven common respiratory viruses in ARI patients in southern China.
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| http://dx.doi.org/10.1016/j.ijid.2020.06.051 | DOI Listing |
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