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The Role of Thickening Agent Proportions in Optimizing Nanoemulsion Gel for Dermatophytosis Treatment.
Int J Nanomedicine
January 2025
College of Animal Science, Guizhou University, Guiyang, Guizhou, People's Republic of China.
Background: Adjusting thickening agent proportions in nanoemulsion gel (NG) balances its transdermal and topical delivery properties, making it more effective for dermatophytosis treatment.
Methods: Carbomer 940 and α-pinene were used as model thickening agent and antifungal, respectively. A series of α-pinene NGs (αNG1, αNG2, αNG3) containing 0.
Experimental Study of Carbonation and Chloride Resistance of Self-Compacting Concretes with a High Content of Fly Ash and Metakaolin, with and Without Hydrated Lime.
Materials (Basel)
January 2025
Federal Institute of Education, Science and Technology of Rio Grande do Norte (IFRN), São Gonçalo do Amarante 59291-727, Brazil.
The durability of reinforced concrete is associated with several factors that can trigger the corrosion of reinforcement bars. Among these factors, the most significant are chloride-ion attack and carbonation. This study evaluated, through accelerated testing, self-compacting concretes (SCCs) with reduced cement content in binary, ternary, and quaternary mixtures using high-early-strength Portland cement, fly ash (FA), metakaolin (MK), and hydrated lime (HL).
View Article and Find Full Text PDFMonitoring and optimization of the microenvironment in a gravity-driven microfluidic system placed on a slow-tilting table.
J Biosci Bioeng
January 2025
Department of Bioengineering, Nagaoka University of Technology, 1603-1 Kamitomioka-machi, Nagaoka, Niigata 940-2188, Japan; Department of Science of Technology Innovation, Nagaoka University of Technology, 1603-1, Kamitomioka-machi, Nagaoka, Niigata, 940-2188 Japan. Electronic address:
Gravity-driven microfluidic chips offer portability and flexibility in different settings because pumps and connecting tubes are unnecessary for driving fluid flow. In a previous study, human induced pluripotent stem cells were cultured using gravity-driven microfluidics, with the liquid flow rate regulated by a tilting table. However, instability in cell culture has been observed, occasionally leading to cell death owing to unknown causes.
View Article and Find Full Text PDFImpact of aeration on plant growth-promoting rhizobacteria assisted phytoremediation capability of arsenic in artificial wetland system.
Int J Phytoremediation
January 2025
Department of Land Management, Faculty of Agriculture, Universiti Putra Malaysia, Serdang, Malaysia.
The increasing demand for sustainable, robust, and cost-efficient arsenic (As) treatment techniques strengthens the implementation of new constructed wetland (CW) designs like aerated CWs in the agricultural sector. The aim was to assess and contrast the influence of various aeration rates on As elimination in subsurface flow CW utilizing plants for treating As-polluted sand. This study consisted of an experiment with 16 subsurface flow CW, operating at different As concentrations of 0, 5, 22, and 39 mg kg and aeration rates of 0, 0.
View Article and Find Full Text PDFElucidating the roles of voltage sensors in Na1.9 activation and inactivation through a spider toxin.
Biochim Biophys Acta Gen Subj
January 2025
The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, 410081, Hunan, China; Peptide and small molecule drug R&D platform, Furong Laboratory, Hunan Normal University, Changsha 410081, Hunan, China; Institute of Interdisciplinary Studies, Hunan Normal University, Changsha 410081, Hunan, China. Electronic address:
The gating process of voltage-gated sodium (Na) channels is extraordinary intrinsic and involves numerous factors, such as voltage-sensing domain (VSD), the N-terminus and C-terminus, and the auxiliary subunits. To date, the gating mechanism of Na channel has not been clearly elucidated. Na1.
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