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http://dx.doi.org/10.1016/j.ajog.2020.06.026 | DOI Listing |
World J Cardiol
December 2024
Department of Cardiology, Dayanand Medical College and Hospital, Ludhiana 141001, Punjab, India.
Perioperative management of antiplatelet therapy involves a delicate balancing of the risk of periprocedural blood loss with the cardiovascular and thrombotic risk to the patient. Due to the unique nature of neurosurgery, perioperative bleeding may have devastating consequences and cause major morbidity and mortality. The recommendation to discontinue aspirin prior to major neurosurgical procedures rests upon conventional practice, expert consensus with priority given to avoidance of any major bleed.
View Article and Find Full Text PDFEur Urol Oncol
December 2024
Department of Urology, Jules Bordet Institute and Erasme Hospital, Hôpital Universitaire de Bruxelles, Brussels, Belgium. Electronic address:
Categorization of patients according to their characteristics may simplify decision-making, but it fails to account for the continuous nature of risk and individual variability. Artificial intelligence has the ability to handle more complex continuous data for more precise, individualized recommendations, but several challenges must be overcome to unlock this potential.
View Article and Find Full Text PDFAnal Chem
December 2024
Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, College of Chemistry and Chemical Engineering, Linyi University, Linyi 276000, China.
To answer the call for effective and timely intervention in cardiovascular diseases (CVDs), the development of fluorescent probes that can precisely identify atherosclerotic plaques, the root cause of various fatal CVDs, is highly desirable but remains a great challenge. Herein, by integrating bis(trifluoromethyl)benzyl and phenothiazine into the coumarin matrix, a robust fluorescent probe, NOR1, has been developed. NOR1 responds sequentially to lipid droplets (LDs) and HClO via fluorescence turn-on and ratiometric readouts, respectively, with a fast response rate (within 70 s for LDs and 80 s for HClO), excellent sensitivity (detection limit: 0.
View Article and Find Full Text PDFReg Anesth Pain Med
December 2024
Anesthesiology, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India
BMJ Open Diabetes Res Care
December 2024
Endocrinology, Leiden Universitair Medisch Centrum, Leiden, Netherlands.
Introduction: Lifestyle determinants of 2-hour glucose concentration in people with type 2 diabetes and interindividual differences need to be identified.
Research Design And Methods: 38 participants with type 2 diabetes, treated with lifestyle advice and/or metformin, tracked their physical activity, sleep and dietary intake, while continuously monitoring interstitial glucose concentrations for 11 periods of four consecutive days each. A linear mixed-effects model was used to quantify the effect of sleep, stress, current glucose, carbohydrate intake and exercise on glucose levels 2 hours later.
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