AI Article Synopsis
- A new mixing medical device was created using Shirasu porous glass and Millipore membrane to make a water-in-oil-in-water (WOW) emulsion quickly for treatment of liver cancer (HCC).
- Toxicity studies with rabbits and pigs showed no side effects when using a single dose of BSH-entrapped WOW emulsion through intra-arterial injection.
- The goal is to advance to preclinical and clinical studies to evaluate the B compound as a multidisciplinary treatment for HCC.
Article Abstract
We developed a mixing medical device by attaching Shirasu porous glass Millipore membrane to prepare water-in-oil-in-water (WOW) emulsion in a shorter time to be applied as B-entrapped WOW emulsion for hepatocellular carcinoma (HCC) treatment. Single-dose toxicity studies by intra-arterial injection of BSH-entrapped WOW were performed in rabbits and pig, and no side effects were observed. We hope to proceed to the preclinical and clinical studies for further evaluation of B compound as multidisciplinary treatments for HCC.
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| http://dx.doi.org/10.1016/j.apradiso.2020.109202 | DOI Listing |
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