AI Article Synopsis
- * A retrospective observational study analyzed data from seven reference hospitals, covering a population of over 3 million adults, and identified 369 patients with CSU unresponsive to antihistamines.
- * The study found a prevalence of refractory CSU at 0.0012%, which is lower than previous estimates and indicates variations between hospital regions; it also highlights the need for further research to better identify CSU patients nationally.
Article Abstract
Chronic urticaria (CU) has a devastating effect on the quality of life of patients who suffer from it. The objective of this study is to determine the prevalence of severe chronic spontaneous urticaria (CSU) in adults in eight health areas in Andalucía. A retrospective observational study from January 2019 to December 2019 was conducted with the participation of seven reference hospitals that were analyzed, including a total reference population of 3 159 001 individuals ≥18 years. The analysis was carried out on the characteristics of the population and the estimated prevalence. In total, 369 patients with a diagnosis of CSU refractory to antagonist of histamine were registered. We have found a prevalence of refractory patients of 0.0012% (95% CI 0.0010%-0.0013), ranging from 0.006% to 0.02%. The present study has helped to describe the prevalence and characteristics of patients with severe urticarial. The prevalence is lower than previously reported. We have observed differences between hospital areas. There will be a new line of research at the national level to help improve the identification of patients with CSU.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/dth.13866 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comprehension of the adapted Urticaria Activity Score measure and patient guidance document: qualitative interviews with adults and adolescents with chronic spontaneous urticaria.
J Patient Rep Outcomes
December 2024
Institute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Paul-Ehrlich-Haus, Hindenburgdamm 30, 12203, Berlin, Germany.
Objective: A key component of determining that a patient-reported outcome (PRO) measure is fit-for-purpose is to ensure that respondents understand its instructions and items. Any modification to a measure should be evaluated for relevance and understandability. The objective of the study was to assess comprehension of the adapted Urticaria Activity Score (UAS) questionnaire among adolescents aged populations with chronic spontaneous urticaria (CSU) and the modification to UAS question 2 to include patient-friendly terminology "wheals (hives).
View Article and Find Full Text PDFDistinct IgE sensitization profiles in chronic urticaria: a comparative study with classic allergic diseases.
Front Immunol
December 2024
Department of Dermatology, Southwest Hospital, Army Medical University, Chongqing, China.
Article Synopsis
- - Chronic urticaria (CU) is linked to atopy, indicated by IgE sensitization, but specific information on its characteristics in CU is limited.
- - An analysis of 1149 patients revealed 33.1% of CU patients had positive specific IgE and 49.0% had elevated total IgE, showing higher rates than healthy controls but lower than classic allergic diseases.
- - The findings suggest CU patients have a distinct IgE sensitization profile that differs from traditional allergic diseases, highlighting the need for further research into its underlying causes and clinical implications.
Clinical burden, treatment, and disease control in patients with chronic spontaneous urticaria: Real-world evidence.
Ann Allergy Asthma Immunol
December 2024
University of Miami, Coral Gables, Florida.
Background: Chronic spontaneous urticaria (CSU) is an unpredictable inflammatory skin condition with substantial clinical burden that affects 0.23-0.78% of the United States population.
View Article and Find Full Text PDFMedication adherence in allergic diseases and asthma: a literature review.
Front Pharmacol
December 2024
Department of Internal Medicine, Asthma and Allergy, Medical University of Lodz, Lodz, Poland.
Patients' collaboration with healthcare providers, along with their individual dedication to follow medical recommendations, is a crucial component of effective therapy in chronic diseases. If a patient fails to fill their prescription, administers the medication improperly in terms of method and/or dosage, misses follow-up visits, or discontinues the treatment for any reason, these lapses can adversely affect disease management, impairing the effectiveness of symptom relief and prevention of progression and complications. A comparable situation pertains to allergic diseases, which require long-term and consistent treatment to achieve symptom alleviation and control.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!