Purpose: The aim of this work was to characterize the dosimetric properties of the PTW microDiamond (60019) single crystal synthetic diamond detector (DD) in kilovoltage x-ray beams. The following characteristics were addressed in this study: required preirradiation dose, dose-rate linearity, energy dependence, and percent depth dose response of the DD.
Methods: UWADCL x-ray beams, characterized by NIST-traceable ionization chambers, were used in this study. Preirradiation dose required by the DD, in order to stabilize the detector's response to within 0.1%, was quantitated. Dose-rate dependence was also investigated using the UW250-M and UW50-M beams, where the dose rate was varied by changing the tube current. and calibration coefficients for all the available M series beams at UWADCL were obtained to determine the energy dependence of the DD, Diode E, Diode P, and P11 parallel-plate ionization chamber. A custom-built water tank was utilized to measure the percent depth dose (PDD) response of the DD, Diode E, Diode P, and P11 chamber in UW250-M, UW100-M, and UW50-M beams. The measured PDD response of the detectors was compared with the simulated PDD data using EGSnrc Monte Carlo code.
Results: A 1.5 Gy dose-to-water or air-kerma was found to be sufficient for the given DD's response to stabilize to within 0.1% in all of the beams used in this study. The dose-rate dependence parameter, Δ, was found to be 1.00 ± 0.02 and 1.016 ± 0.05 for the UW250-M and UW50-M beams, respectively. Relative to the Co calibration coefficients, the DD was found to under-respond relative to calculated absorbed dose to water response and over-respond relative to the calculated air-kerma response in the M-series beams. Agreement of 1.5% was found between the measured PDD values and Monte Carlo simulated PDD values for UW250-M, UW100-M, and UW50-M beams.
Conclusions: In order to stabilize the response, the DD needs a preirradiation dose, which is unique to every DD. A linear relationship between detector response and dose rate was found within the evaluated uncertainty. An energy dependence of the DD was studied, which is more pronounced in the low-energy beams and can be partially attributed to the metal contact material around the sensitive volume of the DD. Overall, the DD was found to be suitable for kilovoltage x-ray dosimetry.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1002/mp.14330 | DOI Listing |
PeerJ
January 2025
Department of Oncology, Cancer Center, Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine, Southern Medical University, Guangzhou, China.
Purpose: The purpose of this study was to determine the efficacy and safety of low-dose radiotherapy (LDR) for postoperative local chest wall recurrence of breast cancer.
Methods: The records of 52 patients with postoperative local chest wall recurrent breast cancer treated at our cancer center from January 2019 to December 2022. The t-test was used to compare the means of the LDR group and non LDR group.
Appl Radiat Isot
November 2024
Departamento de Investigación en Física, Universidad de Sonora, Apartado Postal 5-088, Hermosillo, Sonora 83190, Mexico. Electronic address:
The non-thermoluminescence afterglow-based dosimetry performance of self-agglomerating pellet-shaped CaSO:Dy phosphors synthesized through a low-cost, environmentally friendly method is first reported. Thermoluminescence (TL) and afterglow (AG) were analyzed in samples exposed to beta particle irradiation in the dose range from 0.06 to 8.
View Article and Find Full Text PDFMater Horiz
November 2024
College of Materials Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 211106, China.
The precise, rapid and direct visualization of 3D topographical dose in the target tissue that is crucial for effective radiation therapy remains a challenge. Herein, by combining hydrogel photonic crystals with film stacking or 3D printing, a 3D radiochromic dosimeter with a dose sensitivity of up to 10 nm Gy, a spatial resolution <50 μm, and the ability to detect complex 3D topographical dose distribution was proposed for clinical radiation dose verification. The sensitivity and response range of the dosimeter by radiation-induced polymer cross-linking and consequent Bragg wavelength shift can be tuned the solid content and extent of acrylate modification.
View Article and Find Full Text PDFPLoS One
November 2024
Division of Radioprotectants, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, United States of America.
Multiple accidents in nuclear power plants and the growing concerns about the misuse of radiation exposure in warfare have called for the rapid determination of absorbed radiation doses (RDs). The latest findings about circulating microRNA (miRNAs) using several animal models revealed considerable promises, although translating this knowledge to clinics remains a major challenge. To address this issue, we randomly divided 36 nonhuman primates (NHPs) into six groups and exposed these groups to six different radiation doses ranging from 6.
View Article and Find Full Text PDFSichuan Da Xue Xue Bao Yi Xue Ban
September 2024
( 214400) Jiangyin Clinical College, Xuzhou Medical University, Wuxi 214400, China.
Objective: Radioactive intestinal injury is a common complication during radiotherapy of tumors. The aim of this study is to observe the effect of ionizing radiation on short-term changes in intestinal bile acids and to investigate the radioprotective effect of bile acids on intestinal cells.
Methods: A rat model of small intestinal injury was constructed by exposing the abdomen of the rats to daily irradiation at 2 Gy for 4 d in succession.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!