3D organoid T-cell differentiation from a few hundred peripheral blood CD34 cells was successfully achieved. 3D organoid T-cell differentiation could help physicians distinguish intrinsic from extrinsic defects underlying a clinical SCID phenotype.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322955PMC
http://dx.doi.org/10.1182/bloodadvances.2020001736DOI Listing

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