Objective: Secondary interpretations of imaging studies performed at another facility are increasingly common in radiology, particularly emergency radiology. While data suggests there are often discrepancies found between original and secondary reports, the benefit from the clinician perspective is unclear.
Methods And Materials: An anonymous electronic survey on secondary interpretations was circulated to 58 attending adult emergency physicians and trauma surgeons at a Level I trauma center from March 2018 to April 2018. Chi-squared testing was used for statistical analysis.
Results: 80.8% of respondents requested secondary interpretations either "always" or "most of the time." Over half of the respondents cited trust in the house radiologist interpretation as the primary reason for secondary interpretation requests. 92.3% and 84.6% of respondents felt that the ability to obtain second interpretations improves patient care and facilitates disposition, respectively. 88.5% of respondents reported reduced imaging utilization due to secondary reads. When presented with conflicting interpretations, all trauma surgeons would rely on the in-house interpretation, whereas 50% of the emergency physicians would pursue further imaging (p < 0.05). 96.2% of respondents were uncertain about insurance coverage of secondary interpretations, but 73.1% would continue to order them, regardless.
Conclusion: Secondary reads were heavily utilized, felt to influence patient care, reduced additional imaging and aided in disposition, suggesting clinical benefit. When presented with conflicting reports, trauma surgeons would rely on the in-house interpretation whereas emergency physicians more often opted to pursue additional imaging. Most respondents would still request secondary interpretations despite being unaware of insurance coverage for these interpretations.
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http://dx.doi.org/10.1016/j.clinimag.2020.05.036 | DOI Listing |
Foods
December 2024
Hunan Agriculture Product Processing Institute, Hunan Academy of Agricultural Sciences, Changsha 410125, China.
'Chachi' (CRC), recognized for its considerable edible and medicinal significance, is a valuable source of metabolites beneficial to human health. This research investigates the metabolic distinctions and antioxidant properties across four different parts of CRC, using multivariate statistical analysis to interpret metabolomic data and network pharmacology to identify potential antioxidant targets and relevant signaling pathways. The results indicate considerable metabolic differences in different parts of the sample, with 1622 metabolites showing differential expression, including 816 secondary metabolites, primarily consisting of terpenoids (31.
View Article and Find Full Text PDFBiomolecules
November 2024
Plant Proteomics and Functional Genomics Group, Department of Biochemistry and Molecular Biology and Soil and Agricultural Chemistry, Faculty of Science, University of Alicante, Carretera San Vicente del Raspeig s/n, 03690 San Vicente del Raspeig, Alicante, Spain.
Plants are a valuable source of specialized metabolites that provide a plethora of therapeutic applications. They are natural defenses that plants use to adapt and respond to their changing environment. Decoding their biosynthetic pathways and understanding how specialized plant metabolites (SPMs) respond to biotic or abiotic stress will provide vital knowledge for plant biology research and its application for the future sustainable production of many SPMs of interest.
View Article and Find Full Text PDFThis study concerns the U/U ratios in environmental samples collected in the Pamir region (Central Asia). Cryoconite (a supra-glacial sediment), soil and river water were sampled in the Muztagh Ata Glacier Basin, a secondary basin belonging to Gaizi River watershed. The aim of the research is to assess the impact of anthropic nuclear activities in such a remote area, being the U/U ratio highly sensitive to anthropogenic disturbances.
View Article and Find Full Text PDFEClinicalMedicine
October 2024
Centre for Psychedelic Research, Division of Psychiatry, Department Brain Sciences, Imperial College London, United Kingdom.
Background: Psilocybin therapy (PT) produces rapid and persistent antidepressant effects in major depressive disorder (MDD). However, the long-term effects of PT have never been compared with gold-standard treatments for MDD such as pharmacotherapy or psychotherapy alone or in combination.
Methods: This is a 6-month follow-up study of a phase 2, double-blind, randomised, controlled trial involving patients with moderate-to-severe MDD.
EClinicalMedicine
December 2024
Nottingham Digestive Diseases Centre (NDDC), Translational Medical Sciences, School of Medicine, University of Nottingham, NG7 2UH, UK.
Background: Despite the availability of various pharmacological and behavioural interventions, alcohol-related mortality is rising. This systematic review aimed to critically evaluate the existing literature on the association between glucagon-like peptide-1 receptor agonists use (GLP-1 RAs) and alcohol consumption.
Methods: Electronic searches were conducted on Ovid Medline, EMBASE, PsycINFO, clintrials.
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