We investigated the state of artificial intelligence (AI) in pharmaceutical research and development (R&D) and outline here a risk and reward perspective regarding digital R&D. Given the novelty of the research area, a combined qualitative and quantitative research method was chosen, including the analysis of annual company reports, investor relations information, patent applications, and scientific publications of 21 pharmaceutical companies for the years 2014 to 2019. As a result, we can confirm that the industry is in an 'early mature' phase of using AI in R&D. Furthermore, we can demonstrate that, despite the efforts that need to be managed, recent developments in the industry indicate that it is worthwhile to invest to become a 'digital pharma player'.
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http://dx.doi.org/10.1016/j.drudis.2020.06.002 | DOI Listing |
Nat Food
January 2025
School of Biological Sciences, University of Canterbury, Christchurch, New Zealand.
For commercial viability, cultivated meats require scientifically informed approaches to identify and manage hazards and risks. Here we discuss food safety in the rapidly developing field of cultivated meat as it shifts from lab-based to commercial scales. We focus on what science-informed risk mitigation processes can be implemented from neighbouring fields.
View Article and Find Full Text PDFSci Total Environ
January 2025
Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
Pregnant people are ubiquitously exposed to endocrine-disrupting phthalates through consumer products and food. The placenta may be particularly vulnerable to the adverse effects of phthalates, with evidence from animal models suggesting impacts on placental development and vascularization. We translate this research to humans, examining gestational exposure to phthalates and phthalate replacements in relation to novel markers of chorionic plate surface vascularization.
View Article and Find Full Text PDFSensors (Basel)
October 2024
College of Furnishings and Industrial Design, Nanjing Forestry University, Nanjing 210037, China.
If toddlers are not promptly checked and rescued after falling from relatively high locations at homes, they are at risk of severe health complications. We present a toddler target extraction method and real-time falling alarm. The procedure is executed in two stages: In stage I, a GELAN-integrated YOLOv8 model is used to extract the body features.
View Article and Find Full Text PDFCurr Opin Psychol
August 2024
School of Management, Beijing Institute of Technology, Zhongguancun, Beijing, China.
Historically, the use of technology in organizations has reshaped the nature of human work. In this article, we overview how current waves of artificially intelligent (AI) technologies are following this trend, showing how its uses can both automate and complement human labor, alongside creating new forms of human work. However, AI can also generate both upsides and downsides for workers' experiences, which are dependent upon a range of factors such as how the technology is used and the support employees receive during digital transitions.
View Article and Find Full Text PDFJMIR Pediatr Parent
March 2024
Chair in ICT and Health, Centre for Health and Social Care Research (CESS), University of Vic - Central University of Catalonia (UVic-UCC), Vic, Spain.
Background: The outbreak of COVID-19 has turned the care model of health systems around the world upside down. The health care crisis has led to opportunities for digital health to deliver quality care, and the system has been redirected toward telemedicine. In Catalonia, Spain, as of March 2020, the pattern of visits in primary care pediatric consultations changed, such that face-to-face visits decreased in favor of non-face-to-face visits.
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