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Seroprevalence of SARS-CoV-2 and risk factors for infection among children in Uganda: A serial cross-sectional study.
PLoS One
December 2024
University of California, San Francisco, CA, United States of America.
Background: Understanding COVID-19's impact on children is vital for public health policy, yet age-specific data is scarce, especially in Uganda. This study examines SARS-CoV-2 seroprevalence and risk factors among Ugandan children at two timepoints, along with COVID-19-related knowledge and practices in households, including adult vaccination status.
Methods: Baseline surveys were conducted in 12 communities from April to May 2021 (post-Alpha wave) and follow-up surveys in 32 communities from November 2021 to March 2022 (Omicron wave).
HIV incidence and factors associated with HIV risk among people who inject drugs engaged with harm-reduction programmes in four provinces in South Africa: a retrospective cohort study.
Lancet HIV
December 2024
Community Oriented Primary Care Research Unit, Department of Family Medicine, University of Pretoria, Pretoria, South Africa; TB HIV Care, Cape Town, South Africa.
Article Synopsis
- A study aimed to estimate HIV incidence among people who inject drugs in South Africa using data from harm-reduction services collected between April 2019 and March 2022.
- Of the 31,182 people accessing these services, 10,227 tested for HIV, with 2,402 forming a cohort for analysis, revealing an incidence of 11.8% over 2,306.1 person-years.
- HIV incidence rates were significantly higher in Gauteng and KwaZulu-Natal compared to Eastern and Western Cape, suggesting regional disparities in HIV risk among this population.
Understanding the factors contributing to dengue virus and chikungunya virus seropositivity and seroconversion among children in Kenya.
PLoS Negl Trop Dis
November 2024
Department of Pediatrics, Division of Infectious Diseases, Stanford University, Palo Alto, California, United States of America.
Dengue virus (DENV) and chikungunya virus (CHIKV) are causes of endemic febrile disease among Kenyan children. The exposure risk to these infections is highly multifactorial and linked to environmental factors and human behavior. We investigated relationships between household, socio-economic, demographic, and behavioral risk factors for DENV and CHIKV seropositivity and seroconversion in four settlements in Kenya.
View Article and Find Full Text PDFSARS-CoV-2 seropositivity among healthcare professionals in a rural state.
Antimicrob Steward Healthc Epidemiol
October 2024
Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
Objectives: We evaluated SARS-CoV-2 anti-nucleocapsid (anti-N) seroconversion and seroreversion rates, risk factors associated with SARS-CoV-2 seroconversion, and COVID-19 risk perceptions among academic healthcare center employees in a rural state.
Methods: Among employees aged ≥18 years who completed a screening survey (n = 1,377), we invited all respondents reporting previous COVID-19 (n = 85; 82 accepted) and a random selection of respondents not reporting previous COVID-19 (n = 370; 220 accepted) to participate. Participants completed surveys and provided blood samples at 3-month intervals (T0, T3, T6, T9).
SARS-CoV-2 Antibody Seroprevalence in Gabon: Findings from a Nationwide Household Serosurvey in a Sub-Saharan Africa Country.
Viruses
October 2024
Department of Epidemiology-Biostatistics and Medical Informatics (DEBIM), Faculty of Medicine, University of Health Sciences, Libreville BP 4009, Gabon.
Seroconversion surveys of anti-SARS-CoV-2 antibodies provide accurate estimates of the prevalence of SARS-CoV-2 infections. This nationwide population-based cross-sectional serosurvey aimed to evaluate the prevalence of SARS-CoV-2 antibodies among residents in Gabon and compare the estimated cumulative number of COVID-19 cases with the officially registered number of laboratory-confirmed cases up to December 2021. Households in each province were randomly selected.
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