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http://dx.doi.org/10.17912/micropub.biology.000215 | DOI Listing |
Methods Mol Biol
March 2022
Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, VIC, Australia.
Damaged, dysfunctional, or excess mitochondria are removed from cells via a selective form of macroautophagy termed mitophagy. The clearance of mitochondria during mitophagy is mediated by double-membrane vesicles called autophagosomes, which encapsulate mitochondria that have been tagged for mitophagic removal before delivering them to lysosomes for degradation. A variety of different mitophagy pathways exist that differ in their mechanisms of initiation but share a common pathway of autophagosome formation.
View Article and Find Full Text PDFMicroPubl Biol
January 2020
ACQUIFER is a division of DITABIS, Digital Biomedical Imaging Systems AG, Pforzheim, Germany.
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