Hormesis is a biphasic dose-response relationship with contrasting effects of low versus high doses of stress. Hormesis is rapidly developing in plant science research and has wide implications for risk assessment, stress biology, and agriculture. Here, we explore selected areas of importance to the concept of hormesis and suggest that hormesis is a highly generalizable phenomenon. We address the questions of whether hormesis occurs in high-risk groups or in response to mixtures of stress-inducing agents, whether there is a single biological mechanism of hormesis, and what the temporal features of hormesis are.
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http://dx.doi.org/10.1016/j.tplants.2020.05.006 | DOI Listing |
Physiol Rep
January 2025
Department of Biology, Slippery Rock University of Pennsylvania, Slippery Rock, Pennsylvania, USA.
Melatonin is a multifunctional biomolecule with demonstrated stimulatory, inhibitory, and antioxidant effects, including both receptor-mediated and receptor-independent mechanisms of action. One of its more perplexing effects is the disruption of regeneration in planaria. Head regeneration in planaria is a remarkable phenomenon in which stem cells (neoblasts) migrate to the wound site, proliferate, then differentiate into all functional tissue types within days of injury.
View Article and Find Full Text PDFBiol Lett
January 2025
Department of Entomology, Pennsylvania State University, University Park, PA, USA.
Pollinators face declines and diversity loss associated with multiple stressors, particularly pesticides. Most pollination services are provided by annual bees that undergo winter diapause, and many common pesticides are highly soluble in water and move through soil and plants where bees hibernate and feed, yet the effects of pesticides on pollinators' diapause survival and performance are poorly understood. Pesticides may have complex effects in bees, and some were shown to induce hormetic effects on various traits characterized by high-dose inhibition coupled with low-dose stimulation.
View Article and Find Full Text PDFJ Agric Food Chem
January 2025
Institute of Virology and Biotechnology, State Key Laboratory for Managing Biotic and Chemical Treats to the Quality and Safety of Agro-Products, Key Laboratory of Biotechnology in Plant Protection of Zhejiang Province, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, P. R. China.
Fluoroquinolone antibiotic enrofloxacin (ENR) is frequently detected in agricultural environments. The hormesis and detrimental effects of ENR on crops have been extensively observed. However, the molecular mechanisms underlying these crops' responses to ENR remain limited.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
College of Environmental Science and Engineering, Hunan University, Changsha 410082, PR China. Electronic address:
The production scalability and increasing demand for black phosphorus nanosheets (BPNSs) inevitably lead to environmental leakage. Although BPNSs' ecotoxicological effects have been demonstrated, their indirect health risks, such as inducing increased resistance in pathogenic bacteria, are often overlooked. This study explores the influence of BPNSs on the horizontal gene transfer of antibiotic resistance genes (ARGs) facilitated by the RP4 plasmid, which carries multiple resistance genes.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
College of Plant Protection, Shandong Agricultural University, Taian, Shandong 271018, China. Electronic address:
Previous research on cadmium (Cd) focused on toxicity, neglecting hormesis and its mechanisms. In this study, pakchoi seedlings exposed to varying soil Cd concentrations (CK, 5, 10, 20, 40 mg/kg) showed an inverted U-shaped growth trend (hormesis characteristics): As Cd concentration increases, biomass exhibited hormesis character (Cd5) and then disappear (Cd40). ROS levels rose in both Cd treatments, with Cd5 being intermediate between CK and Cd40.
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