Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314100 | PMC |
http://dx.doi.org/10.1093/ehjci/jeaa181 | DOI Listing |
Int J Cardiol Heart Vasc
December 2024
Department of Cardiovascular Surgery, Guangdong Provincial Hospital of Chinese Medicine, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, the Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou 510120, Guangdong, China.
Background: There are some common pathophysiological risk factors between myocardial infarction and osteoporosis, and the exact relationship between the two is not yet clear. Our study aims to provide evidence on the relationship between myocardial infarction and osteoporosis through the analysis of data from the National Health and Nutrition Examination Survey (NHANES) and Mendelian Randomization (MR) analysis from 2015 to 2018.
Methods: A two-sample MR study using summary statistics from genome-wide association studies (GWAS) was conducted to determine the causal relationship between myocardial infarction and osteoporosis.
Cureus
December 2024
Pediatric Cardiology, Children's Hospital at Montefiore, Bronx, USA.
Brugada syndrome (BrS) is a genetic channelopathy that may predispose to ventricular arrhythmia. It is inherited as an autosomal dominant pattern with incomplete penetrance. Fever can unmask Brugada syndrome in children who have a genetic predisposition.
View Article and Find Full Text PDFCardiovasc Ultrasound
January 2025
Cardiology Department, Hospital de Santa Marta, Unidade Local de Saúde São José, Centro Clínico Académico de Lisboa, Rua de Santa Marta N.º 50, Lisbon, 1169-024, Portugal.
Background: Right ventricular myocardial work (RVMW) assessed by transthoracic echocardiography allows to study the right ventricular (RV) function using RV pressure-strain loops. The assessment of these novel indexes of RVMW has not yet been exten sively studied, namely in pre-capillary pulmonary hypertension (PH) population.
Objectives: to evaluate the relationship between RVMW and invasive indices of right heart catheterization (RHC) in a cohort of patients with group I and group IV PH and to compare with a control group without PH.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
December 2024
Department of Occupational and Radiological Diseases, Changzhou Center for Disease Prevention and Control, Changzhou 213022, China.
This paper reports two cases of occupational severe toxic encephalopathy caused by inhaling excessive nitrogen in an accident. The main reasons are failure to performing field-work standards of limited space operation and emergency rescue. Hypoxia asphyxia is the main pathogenic link of nitrogen toxicity, which can cause brain edema.
View Article and Find Full Text PDFEur J Pharmacol
December 2024
Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450001, China. Electronic address:
Several studies have associated the epitranscriptomic RNA modification of N6-methyladenosine (mA) with cardiovascular diseases; however, how mA modification affects cardiomyocyte pyroptosis after myocardial infarction (MI) remains unknown. Here, we showed that AlkB homolog 5 (ALKBH5), an mA demethylase, is crucial in cardiomyocyte pyroptosis after MI. We used MI rat and mouse models, a cell hypoxia model of rat primary cardiomyocytes (RCMs), and rat embryonic ventricle cell line (H9c2) to explore the functional role of mA modification and ALKBH5 in the heart and cardiomyocytes.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!