The purpose of this work was to compare the measured red-cell volume (RCV) using sodium pertechnétate [RCV-Tc] compared to the reference technique using sodium radiochromate [RCV-Cr] and to assess the influence of technetium-99 elution on the RCV-Tc value. Ten patients had simultaneous measurements of RCV-Tc and RCV-Cr. Elution of Tc-99m from red blood cells was 2.9% and led to an average overestimation of RCV-Tc of 3.7%. The introduction of individual tracer elution rates in the RCV-Tc calculation corrects this overestimation.
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