Interethnic differences in the prevalence of main cardiovascular pharmacogenetic biomarkers.

Pharmacogenomics

Federal State Budgetary Educational Institution of Further Professional Education "Russian Medical Academy of Continuous Professional Education" of The Ministry of Healthcare of The Russian Federation, Barrikadnaya Str., 2/1, Bldg. 1, Moscow, 125993, Russian Federation.

Published: July 2020

The aim of this study was to determine the prevalence of , , , , and genes polymorphisms among residents of the Volga region (Chuvash and Mari) and northern Caucasus (Kabardins and Ossetians). The study involved 845 apparently healthy volunteers of both sexes of the four different ethnic groups living in the Russian Federation: 238 from the Chuvash ethnic group, 206 Mari, 157 Kabardins and 244 Ossetians. Significant differences were identified in allele frequency of , , , , and genes polymorphisms between the Chuvash and Kabardins, Chuvash and Ossetians, Mari and Kabardians, Mari and Ossetians.

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http://dx.doi.org/10.2217/pgs-2020-0005DOI Listing

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