Vasopressor for refractory septic shock: dexmedetomidine could help decrease norepinephrine requirements.

Minerva Anestesiol

Department of Resuscitation and Intensive Care, Hospices Civils de Lyon, Lyon, France.

Published: August 2020

Download full-text PDF

Source
http://dx.doi.org/10.23736/S0375-9393.20.14505-XDOI Listing

Publication Analysis

Top Keywords

vasopressor refractory
4
refractory septic
4
septic shock
4
shock dexmedetomidine
4
dexmedetomidine help
4
help decrease
4
decrease norepinephrine
4
norepinephrine requirements
4
vasopressor
1
septic
1

Similar Publications

Objective: To retrospectively compare and report vasopressor duration and mortality of septic dogs with hypotension refractory to vasopressor administration (presumed critical illness-related corticosteroid insufficiency [CIRCI]) treated with or without dexamethasone sodium phosphate (DxSP).

Design: Retrospective study (2017-2022).

Setting: Tertiary referral and teaching hospitals.

View Article and Find Full Text PDF

Haemodynamic management of septic shock.

Burns Trauma

January 2025

Australian and New Zealand Intensive Care-Research Centre, Monash University School of Public Health and Preventive Medicine, 553 St Kilda Road, Melbourne VIC 3004, Australia.

Septic shock is a significant challenge in the management of patients with burns and traumatic injuries when complicated by infection, necessitating prompt and effective haemodynamic support. This review provides a comprehensive overview of current strategies for vasopressor and fluid management in septic shock, with the aim to optimize patient outcomes. With regard to vasopressor management, we elaborate on the pharmacologic profiles and clinical applications of catecholamines, vasopressin derivatives, angiotensin II, and other vasoactive agents.

View Article and Find Full Text PDF

Background: Direct mechanical ventricular actuation (DMVA) with the Anstadt cup is effective for non-blood-contacting biventricular support. Pneumatic regulation of a silicone device augments ventricular pump function. Vacuum attachment facilitates diastolic augmentation critical for biventricular support.

View Article and Find Full Text PDF

Myxoedema coma is a rare medical emergency, presenting even less commonly without sepsis and with the diagnosis of distributive shock. Reports of catecholamine-refractory shock are scarce. This report describes the case of a 54-year-old male, who presented to the emergency department with altered mental status.

View Article and Find Full Text PDF

Introduction: Immunotherapy has transformed cancer treatment, particularly with immune checkpoint inhibitors and chimeric antigen receptor T-cell therapy. Despite their efficacy, these therapies can induce cardiotoxicity, presenting significant clinical challenges. Immune checkpoint inhibitors can cause myocarditis; pericarditis; arrhythmias; and myocardial infarction through immune-mediated inflammation.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!