The study of clinical and biochemical processes in the oral cavity determined changes in the entire biochemical spectrum of the oral cavity in 132 patients aged 20-40 years with various forms of periodontitis. Similar follow-ups were divided into three groups in the main group with mild to moderate severity of periodontitis with a 10-day intake of radon, 43 patients were united into the control group with no pathological changes in periodontal tissue however. Inhalation and rinsing with radon-containing water causes a decrease in LDH levels in the oral cavity. In patients with mild severity it decreased by 1.29 times, and with moderate severity - by 1.16 times in the main group. The difference is statistically significant (p<0.01). which leads to a decrease in oxidative processes in the oral fluid and the restoration of the fermentation spectrum. As it is known, lactate hydrogenase is an indicator of anaerobic processes and, amylase change and the oral cavity PH, as well as the development of different forms of severity of periodontitis. In our case, the treatment with Tskaltubo water as an antioxidant medicine levels all these processes. Only in case of rinses with water of Tskaltubo, these changes are less pronounced, and in case of both inhalation and rinses they are more pronounced.

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