AI Article Synopsis
- Recent advancements have been made in understanding the genetic factors behind certain cardiac conditions in Arabians and racehorses, like ventricular septal defects and atrial fibrillation.
- Despite strong indicators of a genetic basis, no studies have examined genetic contributions to aortic rupture in Friesians or atrioventricular block in donkeys.
- Ongoing developments in genetic research are bringing us closer to identifying the specific mutations related to inherited cardiac diseases in equids.
Article Abstract
There have been some advances in understanding the genetic contribution to ventricular septal defects in Arabians, sudden death in racehorses, and atrial fibrillation in racehorses. No genetic analyses have been published for aortic rupture in Friesians or atrioventricular block in donkeys despite strong evidence for a genetic cause. To date, no genetic mutation has been identified for any equid cardiac disease. With the advancement of genetic tools and resources, we are moving closer to discoveries that may explain the heritable basis of inherited equid cardiac disease.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.cveq.2020.03.004 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Behavioral Signature of Equine Gastric Discomfort? Preliminary Retrospective Clinical Observations.
Animals (Basel)
January 2025
Havemeyer Equine Behavior Laboratory, Section of Reproduction and Behavior, Department of Clinical Studies, University of Pennsylvania School of Veterinary Medicine, New Bolton Center, Kennett Square, PA 19348, USA.
Gastric ulcer disease and other potentially painful gastric conditions are among the most common afflictions adversely affecting the welfare of domestic equids. A large percentage of affected animals may not display the classic signs of gastric disease, such as unexplained weight loss, poor hair coat, and inappetence until the disease becomes severe. As a clinical service within our equine referral hospital, we routinely evaluate 24-h video recorded samples of horses to assist clinicians in identifying subtle discomfort and potential sources or to scan for infrequent neurologic or cardiac-related behavioral events.
View Article and Find Full Text PDFTorsemide can be used for long-term management of congestive heart failure in equids: a description of 12 cases (2019-2024).
J Am Vet Med Assoc
January 2025
1New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA.
Objective: Information about congestive heart failure (CHF) treatment in the horse is limited. Torsemide, an oral loop diuretic, is increasingly used in humans, dogs, and cats with CHF. Torsemide is well absorbed and induces diuresis in healthy horses, and its use in a horse with CHF has been reported.
View Article and Find Full Text PDFCardiac Disease Related to Primary Hyperthyroidism in a 20-Year-Old Mule.
Animals (Basel)
June 2024
Department of Clinical Sciences, Cornell University, Ithaca, NY 14850, USA.
Primary hyperthyroidism is a rarely diagnosed endocrinopathy in equids and there have been no previous reports of structural and functional cardiac changes associated with hyperthyroidism in these species. This case report investigates a 20-year-old mule gelding that presented for a three-month history of thin body condition despite polyphagia, with a heart murmur and elevated free and total thyroid hormone concentrations. On presentation, physical exam revealed a body condition score of two out of nine, persistent tachycardia, pansystolic heart murmur and firm bilateral ventral proximal cervical masses.
View Article and Find Full Text PDFInsulin, but not adiponectin, is detectable in equine saliva using an automated, commercial assay.
Equine Vet J
March 2024
Department of Clinical Sciences and Services, Royal Veterinary College, Hertfordshire, UK.
Background: The hormones insulin and adiponectin are commonly measured in equids because of their involvement in endocrinopathic laminitis. These are currently measured in serum/plasma, although jugular venipuncture can cause stress in some animals and may be impossible in needle-shy individuals. However, both hormones can be measured in saliva in other species.
View Article and Find Full Text PDFBEVA primary care clinical guidelines: Diagnosis and management of equine pituitary pars intermedia dysfunction.
Equine Vet J
March 2024
EMT Consulting, Devon, UK.
Background: Pituitary pars intermedia dysfunction (PPID) is a prevalent, age-related chronic disorder in equids. Diagnosis of PPID can be challenging because of its broad spectrum of clinical presentations and disparate published diagnostic criteria, and there are limited available treatment options.
Objectives: To develop evidence-based primary care guidelines for the diagnosis and treatment of equine PPID based on the available literature.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!